PRODUCTION OF HYBRIDOMAS

杂交瘤的生产

• 批准号: 5201764
• 负责人: R SIRAGANIAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5201764
• 关键词: antiantibody; antibody receptor; antibody specificity; antireceptor antibody; biological signal transduction; hybridomas; immunoglobulin E; membrane proteins; monoclonal antibody; phosphorylation

Hybridomas are being produced which secrete monoclonal antibodies to defined antigen specificity. In the past hybridomas have been selected that recognize the high affinity IgE receptor, its components and associated cell surface proteins that are involved in signal transduction. Monoclonal antibodies to several other cell surface proteins have also been selected. During the last year monoclonal antibodies were produced that recognize phosphorylated proteins.

正在产生的杂交瘤可以分泌抗病毒的单抗 明确的抗原特异性。在过去，杂交瘤是被选择的 识别高亲和力的IgE受体，其成分和 参与信号转导的相关细胞表面蛋白。 抗其他几种细胞表面蛋白的单抗也 已被选中。在过去的一年里，产生了单克隆抗体。 能够识别磷酸化蛋白质的生物。