STUDIES OF HEREDITY AND ENVIRONMENT IN SCHIZOPHRENIA

精神分裂症的遗传和环境研究

• 批准号: 5203660
• 负责人: A F MIRSKY
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5203660
• 关键词: Israel; Scandinavian country; behavioral genetics; child (0-11); child foster care /adoption; family genetics; human subject; interview; longitudinal human study; parent offspring interaction; schizophrenia; socioenvironment; twin /multiplet

This project has been composed of the following studies: (1) An intensive multi-displinary study of a family with MZ quadruplets (daughters) concordant as to schizophrenia but discordant as to severity and outcome; (2) Studies of danish Adoptees and their biological and adoptive families: (3) A study of children (of schizophrenia and control parents) reared in town or kibbutz in Israel. We maintain contact with the quadruplets but have not pursued active studies with them during the past three years. The Danish adoptees are of continuing interest to us and we are preparing additional reports on factors involved in their psychiatric outcome. The Israeli children have been the subject of intensive research efforts and we have conclude a series of behavioral and biological studies with them.

本项目由以下研究组成：(1)密集的 一家系MZ四胞胎(女)的多学科研究 在精神分裂症方面是一致的，但在严重程度和结果上不一致； (2)丹麦被领养人及其生物学和领养研究 家庭：(3)儿童(精神分裂症患者和对照父母)的研究 在以色列的城镇或集体农场长大。我们与政府保持联系 四胞胎，但在过去没有与他们进行积极的研究 三年了。我们对丹麦被领养人继续感兴趣，并 我们正在准备关于其影响因素的补充报告 精神后果。以色列儿童一直是 密集的研究工作，我们已经得出了一系列行为 和他们一起进行生物学研究。