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Determining regulators of ILC3 in mucosal barrier function and immune homeostasis

Determining regulators of ILC3 in mucosal barrier function and immune homeostasis
确定 ILC3 在粘膜屏障功能和免疫稳态中的调节因子
批准号：
nhmrc : 1122277
负责人：
A/Pr Nicholas Huntington
金额：
$48.12万
依托单位：
The Walter and Eliza Hall Institute of Medical Research
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2017
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2017-01-01 至 2019-12-31
来源：
https://researchdata.edu.au/determining-regulators-ilc3-immune-homeostasis/946915
关键词：
DeterminingregulatorsILC3mucosalbarrier

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中文摘要
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英文摘要
Innate lymphoid cells (ILCs) are specialized cells that defend the body against invading microorganisms at the body’s surfaces, mediate pathogen clearance and tissue repair but may also drive inflammatory conditions such as allergic asthma and inflammatory bowel disease. We will investigate the molecular switches that regulate this novel cell type and potentially uncover novel molecules or pathways for therapeutic targets.
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Identification of CIS as a potent checkpoint in NK cell-mediated tumour immunity
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  • 批准号：
    nhmrc : GNT1124784
  • 项目类别：
    Project Grants
  • 资助金额：
    $95.96万
  • 财政年份：
    2017
  • 负责人：
    A/Pr Nicholas Huntington
  • 依托单位：
海外基金