A flow cytometry facility for ocular regenerative medicine
A flow cytometry facility for ocular regenerative medicine
批准号:
MR/L012758/1
负责人:
Robin Ali
金额:
$85.96万
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2013
资助国家:
英国
项目状态:
已结题
起止时间:
2013 至 --
中文摘要
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英文摘要
This funding will establish a UCL Institute of Ophthalmology flow cytometry facility to support the Institute's ocular regenerative medicine programme. The Institute is recognised internationally for its remarkably strong track record in delivery of novel biological therapies for eye disease and stem cell therapy in particular (e.g. first-in-man gene therapy, stem cell therapy for ocular surface disease, stem cell therapy for advanced Stargardt's, stem cell therapy for age-related macular degeneration [AMD] on target for 2013). An in-house cytometry facility with state-of-the-art equipment for analysis and sorting of stem and progenitor cells will to help to maintain UCL Institute of Ophthalmology as a world leading world centre for ocular cell transplantation.
期刊论文(9)
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DOI:
10.1016/j.exer.2016.08.007
发表时间:
2016-10
期刊:
EXPERIMENTAL EYE RESEARCH
影响因子:
3.4
作者:
[Liyanage, Sidath E., Gardner, Peter J., Ribeiro, Joana, Cristante, Enrico, Sampson, Robert D., Luhmann, Ulrich F. O., Ali, Robin R., Bainbridge, James W.]
通讯作者:
Bainbridge, James W.
DOI:
10.1242/dmm.022475
发表时间:
2016-04
期刊:
Disease models & mechanisms
影响因子:
4.3
作者:
[Chu CJ, Gardner PJ, Copland DA, Liyanage SE, Gonzalez-Cordero A, Kleine Holthaus SM, Luhmann UF, Smith AJ, Ali RR, Dick AD]
通讯作者:
Dick AD
DOI:
10.1167/tvst.6.5.10
发表时间:
2017-09
期刊:
Translational vision science & technology
影响因子:
3
作者:
[Gardner PJ, Yazid S, Ribeiro J, Ali RR, Dick AD]
通讯作者:
Dick AD
Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.
低氧诱导因素对于髓样细胞迁移到发炎的小鼠眼中是可剂量的。
DOI:
10.1038/srep40830
发表时间:
2017-01-23
期刊:
Scientific reports
影响因子:
4.6
作者:
[Gardner PJ, Liyanage SE, Cristante E, Sampson RD, Dick AD, Ali RR, Bainbridge JW]
通讯作者:
Bainbridge JW
DOI:
10.3389/fimmu.2018.02023
发表时间:
2018
期刊:
Frontiers in immunology
影响因子:
7.3
作者:
[Nauser CL, Howard MC, Fanelli G, Farrar CA, Sacks S]
通讯作者:
Sacks S
共 7 条
King's/Royal Free/UCL Gene Therapy Innovation Hub
-
批准号:MR/V030191/1
-
项目类别:Research Grant
-
资助金额:$773.14万
-
财政年份:2021
-
负责人:Robin Ali
-
依托单位:
Clinical trial of cone photoreceptor transplantation for the treatment of retinal degeneration
-
批准号:MR/V038559/1
-
项目类别:Research Grant
-
资助金额:$543.51万
-
财政年份:2021
-
负责人:Robin Ali
-
依托单位:
Improving functional connectivity following transplantation of cone photoreceptors
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批准号:MR/T002735/2
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项目类别:Research Grant
-
资助金额:$244.0万
-
财政年份:2020
-
负责人:Robin Ali
-
依托单位:
Improving functional connectivity following transplantation of cone photoreceptors
-
批准号:MR/T002735/1
-
项目类别:Research Grant
-
资助金额:$299.0万
-
财政年份:2019
-
负责人:Robin Ali
-
依托单位:
Clinical trial of gene therapy for the treatment of Leber congenital amaurosis
-
批准号:MR/M015815/1
-
项目类别:Research Grant
-
资助金额:$380.54万
-
财政年份:2015
-
负责人:Robin Ali
-
依托单位:
Optimisation of human ESC-derived photoreceptor cell differentiation
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批准号:MR/M007871/1
-
项目类别:Research Grant
-
资助金额:$142.3万
-
财政年份:2014
-
负责人:Robin Ali
-
依托单位:
Clinical trial of gene therapy for the treatment of achromatopsia
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批准号:MR/K025589/1
-
项目类别:Research Grant
-
资助金额:$274.29万
-
财政年份:2013
-
负责人:Robin Ali
-
依托单位:
Development of stem cell therapy to restore photopic vision
-
批准号:MR/J004553/1
-
项目类别:Research Grant
-
资助金额:$293.85万
-
财政年份:2012
-
负责人:Robin Ali
-
依托单位:
Development of an AAV vector for treatment of inherited retinal dystrophy caused by RPE65 deficiency
-
批准号:MR/J005215/1
-
项目类别:Research Grant
-
资助金额:$38.79万
-
财政年份:2011
-
负责人:Robin Ali
-
依托单位:
Pathology and treatment of mouse models of dominant retinal disease
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批准号:G0801004/1
-
项目类别:Research Grant
-
资助金额:$54.31万
-
财政年份:2008
-
负责人:Robin Ali
-
依托单位:
Development of stem cell therapy for the treatment of retinal degneration
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批准号:G0700438/1
-
项目类别:Research Grant
-
资助金额:$195.02万
-
财政年份:2008
-
负责人:Robin Ali
-
依托单位:
海外基金