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SITAR growth curve analysis - a statistical method to assess longitudinal growth and development data

SITAR growth curve analysis - a statistical method to assess longitudinal growth and development data
SITAR 生长曲线分析 - 一种评估纵向生长和发育数据的统计方法
批准号:
MR/M012069/1
负责人:
Timothy Cole
金额:
$9.25万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2015
资助国家:
英国
项目状态:
已结题
起止时间:
2015 至 --

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中文摘要
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英文摘要
The pattern of growth in individual children, as represented by their growth curve of successive measurements (e.g. weight or height) plotted against age, may be informative about their circumstances at earlier ages, or conversely it may predict their risk of disease later in life, for example heart disease, stroke or type 2 diabetes. To investigate this it is useful to summarise the shape of each individual's growth curve in a simple way, so that its shape can be related to their earlier or later experiences. The SITAR method of growth curve analysis is a recently developed approach that does just this - it summarises each individual growth curve as just three numbers, reflecting respectively their size (i.e. whether they are tall or short, or heavy or light, as compared to others), their growth tempo (i.e. whether they are relatively mature or delayed in their timing of growth, e.g. when girls reach menarche), and velocity (how fast they are growing compared to others, e.g. in puberty). So for example an individual might be relatively tall, with early puberty, and growing relatively fast. In addition SITAR estimates a smooth average growth curve against which each individual's growth pattern can be compared. The surprising thing is that this model explains nearly all of the variability in growth between individuals, so that their size, tempo and velocity can be viewed as a complete summary of their growth pattern. Put another way, when adjusted for size, tempo and velocity all their growth curves look the same (the SITAR acronym mean Super-Imposition by Translation And Rotation). It is then simple to relate the values of size, tempo and velocity in individuals to their earlier or later experiences, and to look for links with their growth pattern.
期刊论文(10)
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会议论文
DOI: 10.1136/archdischild-2014-306399
发表时间: 2015-02
期刊: Archives of disease in childhood
影响因子: 5.2
作者: [Cole TJ, Rousham EK, Hawley NL, Cameron N, Norris SA, Pettifor JM]
通讯作者: Pettifor JM
DOI: 10.1097/ruq.0000000000000460
发表时间: 2019
期刊: Ultrasound quarterly
影响因子: 1.3
作者: [R. Barr]
通讯作者: R. Barr
The Remarkable Life of Frances Wood
弗朗西斯·伍德的非凡一生
DOI: 10.1111/j.1740-9713.2017.01074.x
发表时间: 2017
期刊: Significance
影响因子: --
作者: [Cole T]
通讯作者: Cole T
DOI: 10.1002/ajhb.23054
发表时间: 2018-01
期刊: American journal of human biology : the official journal of the Human Biology Council
影响因子: --
作者: [Cole TJ, Mori H]
通讯作者: Mori H
8
    Statistical methods and applications in growth and development - SITAR, LMS and IOTF
    • 批准号:
      MR/R010692/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $12.29万
    • 财政年份:
      2018
    • 负责人:
      Timothy Cole
    • 依托单位:
    The SITAR method of growth curve analysis for growth assessment in translational medicine and life course epidemiology
    • 批准号:
      MR/J004839/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $10.1万
    • 财政年份:
      2012
    • 负责人:
      Timothy Cole
    • 依托单位:
    Mathematical methods in the assessment of human growth
    • 批准号:
      G0700961/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $45.16万
    • 财政年份:
      2008
    • 负责人:
      Timothy Cole
    • 依托单位:
    国内基金
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      2024Y9049
    • 项目类别:
      省市级项目
    • 资助金额:
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      2024
    • 负责人:
      阮君山
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    含Re、Ru先进镍基单晶高温合金中TCP相成核—生长机理的原位动态研究
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      52301178
    • 项目类别:
      青年科学基金项目
    • 资助金额:
      30.00万元
    • 批准年份:
      2023
    • 负责人:
      夏万顺
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    新型小分子蛋白—人肝细胞生长因子三环域(hHGFK1)抑制破骨细胞及治疗小鼠骨质疏松的疗效评估与机制研究
    • 批准号:
      82370885
    • 项目类别:
      面上项目
    • 资助金额:
      49.00万元
    • 批准年份:
      2023
    • 负责人:
      姚晨
    • 依托单位:
    基于 Klotho 调控 FGF23/SGK1/NF-κB信号通路研究糖尿病肾病血管钙化机制及肾元颗粒干预作用
    • 批准号:
    • 项目类别:
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      --
    • 批准年份:
      2022
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