课题基金 / 基金详情

CORE--SCIENTIFIC

CORE--SCIENTIFIC
核心--科学
批准号：
6112237
负责人：
MICHAEL A BALDWIN
金额：
$18.35万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-07-01 至 2000-06-30
来源：
https://reporter.nih.gov/project-details/6112237
关键词：
SDS polyacrylamide gel electrophoresis animal extract biomedical facility circular dichroism fluorescence spectrometry genetically modified animals high performance liquid chromatography immunological substance in situ hybridization infrared spectrometry interferometry laboratory mouse mass spectrometry nucleic acid chemical synthesis nucleic acid sequence oligonucleotides peptide chemical synthesis polymerase chain reaction prions protein purification protein sequence ultracentrifugation

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中文摘要
翻译
科学核心是为促进科学工作而设立的适度单位
英文摘要
The Scientific Core is a modest unit set up to facilitate the scientific projects within the program. The services and reagents provided by the Scientific Core are purified prions, bioassays, antibodies, synthetic peptides, and neuropathologic evaluations. The bioassay part of the Scientific Core obviously overlaps with the Animal Core. Most of the projects require purified prions, bioassays, antibodies to PrP peptides, and neuropathologic evaluations at least of selected animals. Two of the projects also use synthetic peptides. To provide these services and reagents, Dr. Stephen Dearmond, a skilled neuropathologist, and Dr. Dan Serban, a talented immunologist, are needed. In addition, the skills of Ms. Hana Serban and Ms. Darlene Groth are crucial to the smooth operation of the Scientific Core and the provision of purified prions.
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