CORE--SCIENTIFIC

科学核心是一个适度的单位，旨在促进科学 方案内的项目。 提供的服务和试剂 科学核心是纯化朊病毒，生物测定，抗体，合成 肽和神经病理学评估。 的生物测定部分， 科学核心显然与动物核心重叠。 大部分 项目需要纯化的朊病毒，生物测定，PrP肽的抗体， 以及至少对所选动物的神经病理学评价。 两 项目还使用合成肽。 提供这些服务， 试剂，斯蒂芬·迪尔蒙德博士，一位熟练的神经病理学家，和丹博士 需要一位天才免疫学家塞尔班。 此外， 女士哈娜·塞尔班和达琳·格罗斯女士对顺利运作至关重要 科学核心的核心和纯化朊病毒的供应

The Scientific Core is a modest unit set up to facilitate the scientific projects within the program. The services and reagents provided by the Scientific Core are purified prions, bioassays, antibodies, synthetic peptides, and neuropathologic evaluations. The bioassay part of the Scientific Core obviously overlaps with the Animal Core. Most of the projects require purified prions, bioassays, antibodies to PrP peptides, and neuropathologic evaluations at least of selected animals. Two of the projects also use synthetic peptides. To provide these services and reagents, Dr. Stephen Dearmond, a skilled neuropathologist, and Dr. Dan Serban, a talented immunologist, are needed. In addition, the skills of Ms. Hana Serban and Ms. Darlene Groth are crucial to the smooth operation of the Scientific Core and the provision of purified prions.