DEVELOPMENTAL CONTINUITY OF INDIVIDUAL DIFFERENCES IN REACTIVITY IN MONKEYS

该项目通过以下方式研究灵长类动物的生物行为发展： 恒河猴和卷尾猴的纵向比较研究， 特别强调对不同的个人模式的特点 对环境新奇性的行为和生理反应， 的长期发展后果的问题 不同遗传背景的个体在不同的物理环境中长大， 和社会环境。 在1997财政年度进行的研究（a）查明 3种不同的对新奇事物的典型行为反应集群， 1个月大的恒河猴婴儿;（B）表现出加速发育 在保育院饲养的恒河猴的定向和运动能力 接受必需脂肪酸补充剂的婴儿， 从出生开始的标准配方饮食;（c）具有显著特征 不同饲养条件下恒河猴幼猴行为发育的差异 母亲的慢性CSF浓度系统性不同， 5-HIAA，主要的中枢5-羟色胺代谢物;（d）记录 在求偶和生殖行为上的显著缺陷， 自由放养的恒河猴青少年和年轻成年雄性， 异常低的慢性CSF 5-HIAA浓度;（e）描述了系统性 不同类型的相对发病率之间的关联 攻击行为和CSF水平的5-HIAA和睾酮， 自由放养的恒河猴成年雄性;（f）特征为短， 不同的早期行为和 活动状态曲线和随后的生物行为发育 卷尾猴婴儿和少年的轨迹;以及（g） 证明了个体差异之间的预测关系， 卷尾猴对攻击的典型生物行为反应 婴儿和他们随后的倾向，从事探索和 原型工具使用行为。

This project investigates primate biobehavioral development through comparative longitudinal studies of rhesus and capuchin monkeys, with special emphasis on characterizing individual patterns of differential behavioral and physiological responses to environmental novelty and challenge and on determining long-term developmental consequences for individuals of different genetic backgrounds reared in different physical and social environments. Research carried out during FY97 (a) identified 3 distinctive clusters of prototypical behavioral response to novelty in month-old rhesus monkey infants; (b) demonstrated accelerated development of orienting and motor capabilities in nursery-reared rhesus monkey infants who received supplements of essential fatty acids to their standard formula diets beginning at birth; (c) characterized significant differences in behavioral development among rhesus monkey infants reared by mothers who differed systematically in chronic CSF concentrations of 5-HIAA, the primary central serotonin metabolite; (d) documented significant deficits in courtship and reproductive behavior in free-ranging rhesus monkey adolescent and young adult males with unusually low chronic CSF 5-HIAA concentrations; (e) described systematic associations between the relative incidence of different types of aggressive behavior and CSF levels of 5-HIAA and testosterone in free-ranging rhesus monkey adult males; (f) characterized short- and long-term predictive relationships between different early behavioral and activity state profiles and subsequent biobehavioral developmental trajectories in capuchin monkey infants and juveniles; and (g) demonstrated a predictive relationship between individual differences in prototypic biobehavioral response to challenge among capuchin monkey infants and their subsequent proclivity to engage in exploratory and proto-tool use behaviors.