STATISTICAL ANALYSES FOR GENETIC EPIDEMIOLOGICAL STUDIES

利用DNA标记检测颅面和口腔的基因作图研究 疾病利用了各种各样的统计技术。我们是 制定一个更好地集成这些软件工具的方案。因为有很多人 其中一些程序是在其他地方使用各种计算机编写的 语言和输入格式，将它们与我们的内部数据库集成 将简化分析流程。我们正在不断更新我们的 作为遗传流行病学领域的一套统计分析工具 发展非常迅速，有了改进的方法和计算机 定期提供节目。我们的部分工作还包括 对基础统计研究的调查，如对 软件过程的特定方面与SAS Proc混合， 目的：更好地了解牙科数据的正确应用。 与NIAAA和昆士兰研究所的同事合作 医学研究为我们提供了访问未发布软件的途径 用于基因分析的程序。我们最近已经提供了部分 向NHGRI的同事介绍我们的统计分析软件，并 为员工提供使用这些程序的培训。

Gene mapping studies using DNA markers to detect craniofacial and oral diseases utilize a wide variety of statistical techniques. We are developing a scheme to better integrate these software tools. Since many of these programs were written elsewhere using a variety of computer languages and input formats, integrating them with our internal database will streamline the analysis process. We are constantly updating our suite of statistical analysis tools as the field of genetic epidemiology is under very rapid development, with improved methods and computer programs regularly being made available. Part of our work also involves investigation of basic statistical studies such as an investigation of specific aspects of the software procedure SAS PROC MIXED, with the objective of better understanding proper application to dental data. Collaborations with colleagues at the NIAAA and Queensland Institute of Medical Research have provided us with access to unpublished software programs for genetic analyses. We have recently made available portions of our statistical analysis software to colleagues at the NHGRI and are providing training for their staff in the use of these programs.