CAUSES AND EFFECTS OF SMOKING CESSATION

戒烟的原因和影响

• 批准号: 2452822
• 负责人: S R DIEHL
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2452822
• 关键词: behavioral genetics; blood chemistry; clinical research; human subject; immunoglobulins; smoking cessation

The Studies of the Causes and Effects of Smoking Cessation will be carried out at the Jerry L. Pettis Memorial VA Medical Center in Loma Linda, California in collaboration with Dr. Linda H. Ferry MD, MPH. As a supplement to an ongoing VA protocol, ambulatory veterans from the VA Preventive Medicine Clinic and the VA Stop Smoking Classes will be recruited to participate in this two pronged pilot study to test whether immunoglobulin levels change after smoking cessation and to evaluate possible hereditary influences on smoking behaviors. Personal histories of smoking and biological samples (blood from each recruited patient) will be provided to the MEDIB laboratory for molecular analyses. MEDIB will evaluate the differences between subjects that do versus those that do not succeed in quitting smoking. The study population will consist of approximately 300 (male and female) ambulatory veterans who are enrolled in the ongoing Smoking Cessation Program.

戒烟的原因和效果的研究将是 在Jerry L。佩蒂斯纪念VA医疗中心在洛马 琳达，加州州与博士合作琳达H。费里医学博士，公共卫生硕士。 作为正在进行的VA协议的补充，来自 VA预防医学诊所和VA戒烟课程 将被招募参加这项双管齐下的试点研究， 测试戒烟后免疫球蛋白水平是否发生变化， 评估可能的遗传对吸烟行为的影响。 个人吸烟史和生物样本（每个人的血液） 招募的患者）将被提供给MEDIB实验室， 分子分析MEDIB将评估以下方面的差异： 成功戒烟的受试者与未成功戒烟的受试者 smoking. 研究人群将包括约300名 (male和女性）参加正在进行的 戒烟计划。