EXERCISE EFFECTS--MENTAL AND PHYSICAL HEALTH IN BREAST C

运动对乳房的心理和身体健康影响

• 批准号: 6364753
• 负责人: FRANK M PERNA
• 金额: $ 16.11万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6364753
• 关键词: aerobic exercise; behavioral /social science research tag; body composition; breast neoplasms; clinical research; female; human subject; mental health; physical fitness; psychological aspect of cancer; psychological stressor; quality of life; women's health

Within their lifetime, 1 in 8 women will be diagnosed with breast cancer, and the degree of psychological distress and impairment in physical functioning accompanying diagnoses and treatment have been prospectively related to quality of life (QOL) and morbidity. While prior work suggests that exercise may enhance mental and physical health, the efficacy of exercise to promote psychological and physical functioning has not been adequately assessed nor have factors related to exercise compliance been investigated. Over a 5-year period, we will implement an exercise intervention and evaluate its effects on psychological distress, fitness, body composition, and QOL among stage I and II breast cancer patients. We will also evaluate the pathways which may mediate exercise effects on QOL and assess exercise adherence factors. Women (N =140) drawn from West Virginia University's Mary Babb Randolph Cancer Center and the surrounding communities will be randomly assigned to either a 1-year exercise intervention or a control condition with assessments at baseline, 3, 6, and 12 months. Assessments will consist of a graded exercise test assessing cardiovascular fitness, body composition and strength analyses, and a psychosocial survey assessing psychological distress and QOL for which women will be compensated 40 dollar per assessment. Exercise group participants will be provided individualized walking and resistance training exercise programs inclusive of laboratory monitored and home-based phases. The intervention will also utilize cognitive-behavioral techniques such as contingency planning, goal setting, and self-monitoring to promote exercise adherence. The education-standard of care control group will be provided with general information regarding healthy lifestyle management, but will not receive a formal exercise prescription nor undergo the intervention experience in solidifying and acting on this information. Beyond comprehensively testing the efficacy of a low cost aerobic exercise intervention to promote physical and mental health, the project will also generate information which may be useful for promoting exercise among persons of low income.

在她们的一生中，每8名妇女中就有1名被诊断患有乳腺癌，伴随诊断和治疗的心理困扰和身体功能受损程度与生活质量（QOL）和发病率有前瞻性关系。 虽然以前的工作表明，运动可以提高心理和身体健康，运动的功效，以促进心理和身体功能尚未得到充分的评估，也没有相关的因素进行了调查锻炼的依从性。 在5年的时间里，我们将实施一项运动干预，并评估其对I期和II期乳腺癌患者的心理困扰、健身、身体成分和生活质量的影响。 我们还将评估可能介导运动对QOL影响的途径，并评估运动依从性因素。 从西弗吉尼亚大学玛丽巴布兰多夫癌症中心和周围社区抽取的妇女（N =140）将被随机分配到1年的运动干预或对照组，并在基线、3、6和12个月进行评估。 评估将包括评估心血管健康、身体成分和力量分析的分级运动测试，以及评估心理困扰和QOL的心理社会调查，妇女每次评估将获得40美元的补偿。 将为运动组参与者提供个性化的步行和阻力训练运动计划，包括实验室监测和家庭阶段。 干预还将利用认知行为技术，如应急计划，目标设定和自我监测，以促进锻炼的坚持性。 将向教育标准护理对照组提供有关健康生活方式管理的一般信息，但不会接受正式的运动处方，也不会接受巩固和根据这些信息采取行动的干预经验。 除了全面测试低成本有氧运动对促进身心健康的成效外，该计划亦会提供数据，有助向低收入人士披索运动。