EXERCISE EFFECTS ON MENTAL AND PHYSICAL HEALTH IN BREAST CANCER

运动对乳腺癌患者心理和身体健康的影响

• 批准号: 7606213
• 负责人: FRANK M PERNA
• 金额: $ 0.38万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-01-03 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606213
• 关键词: Academic Medical Centers; Adherence; Behavioral; Body Composition; Boston; Cancer Patient; Cardiovascular system; Caring; Cognitive; Communities; Computer Retrieval of Information on Scientific Projects Database; Condition; Control Groups; Education; Exercise; Exercise stress test; Funding; Goals; Grant; Health; Home environment; Institution; Intervention; Laboratories; Life Style; Low income; Mediating; Mental Health; Monitor; Participant; Pathway interactions; Persons; Phase; Psyche structure; Quality of life; Randomized; Research; Research Personnel; Resistance; Resources; Source; Staging; Standards of Weights and Measures; Surveys; Techniques; Testing; Training; United States National Institutes of Health; Walking; Woman; Women' s Health; base; cancer risk; cost; diet and exercise; experience; fitness; malignant breast neoplasm; mortality; prescription document; prescription procedure; programs; psychological distress; psychosocial; stress management

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Over a 5-year period, we will implement an exercise intervention and evaluate its effects on psychological distress, fitness, body composition, and QOL among stage I and II breast cancer patients. Lastly, we will also evaluate the pathways, which may mediate exercise effects on QOL and assess exercise adherence factors. Women (N=140) drawn from Boston University Medical Center's Women's Health Group and the surrounding communities will be randomly assigned to either a 1-year exercise intervention or a control condition with assessments at baseline, 3, 6, and 12 months. Assessments will consist of a graded exercise test assessing cardiovascular fitness, body composition analysis, strength testing, and a psychosocial survey assesssing psychological distress and QOL for which women will be compensated $160 over four assessments. Exercise group participants will be provided individualized walking and resistance training exercise programs inclusive of laboratory monitored and home-based phases. The intervention will also utilize cognitive-behavioral techniques such as contingency planning, goal setting, and self-monitoring to promote exercise adherence. The education-standard of care control group will be provided with general information regarding healthy lifestyle management (i.e. effects of exercise, diet, and stress management), but will not receive a formal exercise prescription nor undergo the intervention experience in solidifying and acting on this information. Beyond comprehensively testing the efficacy of a low cost exercise intervention to promote physical and mental health, the project will also generate information that may be useful for promoting exercise among persons of low income who are at relatively greater risk for cancer mortality.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 在5年的时间里，我们将实施一项运动干预，并评估其对I期和II期乳腺癌患者的心理困扰、健身、身体成分和生活质量的影响。 最后，我们还将评估可能介导运动对生活质量影响的途径，并评估运动依从性因素。 来自波士顿大学医学中心妇女健康小组和周围社区的妇女（N=140）将被随机分配到1年的运动干预或对照组，并在基线、3个月、6个月和12个月进行评估。 评估将包括评估心血管健康的分级运动测试、身体成分分析、力量测试以及评估心理困扰和生活质量的心理社会调查，女性将在四次评估中获得160美元的补偿。 将为运动组参与者提供个性化的步行和阻力训练运动计划，包括实验室监测和家庭阶段。 干预还将利用认知行为技术，如应急计划，目标设定和自我监测，以促进锻炼的坚持性。 将向教育标准治疗对照组提供有关健康生活方式管理的一般信息（即运动、饮食和压力管理的影响），但不会接受正式的运动处方，也不会接受巩固和采取措施的干预经验。 除了全面测试低成本运动干预措施对促进身心健康的功效外，该项目还将产生可能有用的信息，以促进癌症死亡风险相对较高的低收入人士的运动。