EXERCISE EFFECTS--MENTAL AND PHYSICAL HEALTH IN BREAST C

运动对乳房的心理和身体健康影响

• 批准号: 6412052
• 负责人: FRANK M PERNA
• 金额: $ 17.61万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6412052
• 关键词: aerobic exercise; behavioral /social science research tag; body composition; breast neoplasms; clinical research; female; human subject; mental health; physical fitness; psychological aspect of cancer; psychological stressor; quality of life; women's health

Within their lifetime, 1 in 8 women will be diagnosed with breast cancer, and the degree of psychological distress and impairment in physical functioning accompanying diagnoses and treatment have been prospectively related to quality of life (QOL) and morbidity. While prior work suggests that exercise may enhance mental and physical health, the efficacy of exercise to promote psychological and physical functioning has not been adequately assessed nor have factors related to exercise compliance been investigated. Over a 5-year period, we will implement an exercise intervention and evaluate its effects on psychological distress, fitness, body composition, and QOL among stage I and II breast cancer patients. We will also evaluate the pathways which may mediate exercise effects on QOL and assess exercise adherence factors. Women (N =140) drawn from West Virginia University's Mary Babb Randolph Cancer Center and the surrounding communities will be randomly assigned to either a 1-year exercise intervention or a control condition with assessments at baseline, 3, 6, and 12 months. Assessments will consist of a graded exercise test assessing cardiovascular fitness, body composition and strength analyses, and a psychosocial survey assessing psychological distress and QOL for which women will be compensated 40 dollar per assessment. Exercise group participants will be provided individualized walking and resistance training exercise programs inclusive of laboratory monitored and home-based phases. The intervention will also utilize cognitive-behavioral techniques such as contingency planning, goal setting, and self-monitoring to promote exercise adherence. The education-standard of care control group will be provided with general information regarding healthy lifestyle management, but will not receive a formal exercise prescription nor undergo the intervention experience in solidifying and acting on this information. Beyond comprehensively testing the efficacy of a low cost aerobic exercise intervention to promote physical and mental health, the project will also generate information which may be useful for promoting exercise among persons of low income.

在她们的一生中，八分之一的女性将被诊断出患有乳腺癌，伴随诊断和治疗的心理困扰和身体功能损伤的程度与生活质量（QOL）和发病率前瞻性相关。 虽然之前的研究表明运动可以增强心理和身体健康，但运动促进心理和身体功能的功效尚未得到充分评估，也没有调查与运动依从性相关的因素。 我们将在 5 年的时间内实施运动干预，并评估其对 I 期和 II 期乳腺癌患者的心理困扰、健康、身体成分和生活质量的影响。 我们还将评估可能介导运动对生活质量影响的途径，并评估运动坚持因素。 来自西弗吉尼亚大学 Mary Babb Randolph 癌症中心和周边社区的女性 (N = 140) 将被随机分配到为期 1 年的运动干预组或对照条件组，并在基线、3、6 和 12 个月时进行评估。 评估将包括评估心血管健康、身体成分和力量分析的分级运动测试，以及评估心理困扰和生活质量的社会心理调查，女性每次评估将获得 40 美元的补偿。 运动组参与者将接受个性化的步行和阻力训练运动计划，包括实验室监测和家庭阶段。 干预措施还将利用应急计划、目标设定和自我监控等认知行为技术来促进运动坚持。 护理教育标准对照组将获得有关健康生活方式管理的一般信息，但不会收到正式的运动处方，也不会接受巩固这些信息并采取行动的干预经验。 除了全面测试低成本有氧运动干预措施促进身心健康的功效外，该项目还将生成可能有助于促进低收入人群锻炼的信息。