NEURAL SIGNALS AT THE SPATIOTEMPORAL EDGE

时空边缘的神经信号

• 批准号: 6164662
• 负责人: Stephen Louis Macknik
• 金额: $ 3.92万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-03-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6164662
• 关键词: Macaca mulatta; behavioral /social science research tag; lateral geniculate body; neural inhibition; neurophysiology; perceptual maskings; psychophysics; visual perception

This proposal outlines a single year of research to examine the strength of neural signals within the lateral geniculate nucleus of awake behaving primates, in response to spatiotemporal edges. Human psychophysical studies using illusions of invisibility (such as forward and backward masking) have shown that it is the edges of masks in space, as well as the timing of their onset and termination (their temporal edges), that are most effective in rendering targets invisible. Neural signals important to masking are therefore most likely to be associated with the mask s spatiotemporal edge. The proposed experiments will examine the neural correlates of these edge effects (both spatial and temporal) in the lateral geniculate nucleus of primates by recording from single-units while displaying stimuli used in previous human psychophysical experiments. These experiments will segregate the spatial edge effects from the temporal edge effects and test them conveyed separately. The results should reveal the relative strength of neural inhibition from the spatiotemporal edge of the mask in comparison with the signal generated in the mask s spatial and temporal interior.

该提案概述了一年的研究，以检查清醒行为灵长类动物外侧膝状体核内神经信号的强度，以响应时空边缘。人类心理物理学研究使用了隐形错觉（如向前和向后掩蔽），研究表明，掩蔽在空间中的边缘，以及它们开始和结束的时间（它们的时间边缘），在使目标隐形方面最有效。 因此，对掩蔽很重要的神经信号最有可能与掩蔽的时空边缘相关联。 拟议的实验将检查这些边缘效应（空间和时间）在灵长类动物的外侧膝状体核的神经相关记录从单一的单位，同时显示在以前的人类心理物理学实验中使用的刺激。 这些实验将空间边缘效应从时间边缘效应中分离出来，并分别测试它们。 结果应该揭示相对强度的神经抑制从掩模的时空边缘相比，在掩模的空间和时间的内部产生的信号。