Dissecting the pseudoexfoliation syndrome with complementary genetic, proteomic and biophysical strategies

用互补的遗传、蛋白质组学和生物物理策略剖析假性剥脱综合征

• 批准号: nhmrc : 535044
• 负责人: A/Pr Kathryn Burdon
• 金额: $ 32.7万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dissecting-pseudoexfoliation-syndrome-biophysical-strategies/81543
• 关键词: Dissecting; pseudoexfoliation; syndrome; complementary; genetic

Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.

假性脱落综合征（PEX）是一种眼部疾病，眼部有片状物质沉积，大大增加白内障和青光眼的风险，从而导致失明。PEX还与心脏病、中风和动脉瘤有关。PEX患者的白内障手术并发症发生率较高。在这个项目中，我们将确定PEX材料的性质及其形成的原因。这一知识将有助于更好地诊断和治疗PEX，预防相关失明。