A genome-wide association scan to identify genetic risk factors for sight threatening diabetic retinopathy

全基因组关联扫描可识别威胁视力的糖尿病视网膜病变的遗传风险因素

• 批准号: nhmrc : 595918
• 负责人: A/Pr Kathryn Burdon
• 金额: $ 65.49万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genome-wide-association-diabetic-retinopathy/95658
• 关键词: genome; wide; association; scan; identify

Diabetic eye disease is an important complication of diabetes that can lead to blindness. Very little is known about how diabetes causes eye disease, but genetics is known to play a role. We aim to identify genes that contribute to eye disease in diabetes patients. We will compare genes between patients with diabetes with and without severe diabetic eye disease using cutting edge genomic technology. We hope to be able to better predict risk of blindness and to move towards novel treatments.

糖尿病眼病是糖尿病的一个重要并发症，可导致失明。人们对糖尿病如何导致眼病知之甚少，但众所周知，遗传因素起到了一定的作用。我们的目标是识别导致糖尿病患者眼部疾病的基因。我们将使用尖端基因组技术比较患有和不患有严重糖尿病眼病的糖尿病患者之间的基因。我们希望能够更好地预测失明风险，并走向新的治疗方法。