SIMULATIONS OF VORTICES OF EXCITATION WAVES IN CARDIAC TISSUE

在这个项目中，我们的目标是改进设计用于模拟的模型 心脏电脉冲的产生和传递 细胞。该模型被用来研究火药的起爆和爆炸机理。 心脏基础激发波涡旋的维持 快速性心律失常。在后续阶段，如果模型可以 真实地再现激发涡旋，我们将研究如何 可以通过改变膜的功能来终止这种涡流。我们有 使用MPI开发了我们的代码的并行版本。基于我们的 性能测试，使用IBM SP上的32个处理器，需要10 数小时(挂钟)获得一次心动过速发作；即1秒 2 cm x 2的小块心脏组织中的涡旋状活动 厘米。同样的模拟在SPARC上需要8天多一点的时间 10型512型。在支持期间，我们将完善 当前版本的矩阵求逆程序。我们相信它 可以将计算时间除以介于 3和5通过使用适合于 并行化

In this project, we aim at improving a model devised to simulate the generation and transmission of electrical impulses by cardiac cells. This model is used to study the mechanisms of initiation and sustainment of vortices of excitation waves which underlie cardiac tachyarrhythmias. In a subsequent phase, and if the model can realistically reproduce vortices of excitation, we will study how membrane functions can be altered to terminate such vortices. We have developed a parallel version of our code using MPI. Based on our performance tests, using 32 processors on the IBM SP, it will take 10 hours (wall clock) to obtain an episode of tachycardia; i.e. 1 sec of vortex-like activity, in a small piece of cardiac tissue of 2 cm x 2 cm. The same simulation requires a little more than 8 days on a SPARC 10 model 512. During the period of support, we will improve the matrix inversion procedure of the current version. We believe that it is possible to divide the computation time by a factor ranging between 3 and 5 by using a preconditioning procedure suitable for parallelization