Does HIV function as a lipid-raft during infection?

HIV在感染过程中是否起到脂筏的作用？

• 批准号: nhmrc : 488200
• 负责人: A/Pr Anthony Jaworowski
• 金额: $ 40.49万
• 依托单位: Macfarlane Burnet Institute for Medical Research and Public Health
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/does-hiv-function-raft-infection/99632
• 关键词: Does; HIV; function; lipid; raft

The exterior surface of HIV has a layer of lipids (a type of fat), which represents approximately 1-3 of HIV by weight. This layer of lipids may serve as a mechanistic trigger, which enables viral components to be systemically released or dispatched from the main structure post-entry to establish successful infection. Completion of this project will define the role of lipids in this process. This new knowledge will be vital to identify new targets to deter the HIV infection process.

HIV病毒的外表面有一层脂质（一种脂肪），约占HIV病毒重量的1-3。这一层脂质可以作为一种机制触发器，使病毒成分在进入主结构后被系统地释放或派遣，从而建立成功的感染。该项目的完成将确定脂质在这一过程中的作用。这一新知识对于确定新的目标以阻止艾滋病毒感染过程至关重要。