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The role of chemokines in establishing HIV latency

The role of chemokines in establishing HIV latency
趋化因子在建立 HIV 潜伏期中的作用
批准号：
nhmrc : 1002761
负责人：
A/Pr Anthony Jaworowski
金额：
$24.81万
依托单位：
Monash University
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2011
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2011-01-01 至 2013-12-31
来源：
https://researchdata.edu.au/role-chemokines-establishing-hiv-latency/108859
关键词：
rolechemokinesestablishingHIVlatency

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英文摘要
Although antiviral therapy is effective in controlling HIV, therapy must be continued life-long because the virus cannot be cleared from long lived infected CD4+ T cells that are silently or latently infected. In this proposal we will explore the mechanism of how HIV can enter these resting CD4+ T-cells and establish long lived latent infection. Understanding this process may potentially lead to new strategies to cure HIV infection.
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A new monocyte atherogenic phenotype in chronic HIV disease.
  • 批准号：
    nhmrc : GNT1108792
  • 项目类别：
    Project Grants
  • 资助金额：
    $63.2万
  • 财政年份：
    2016
  • 负责人：
    A/Pr Anthony Jaworowski
  • 依托单位：
A new monocyte atherogenic phenotype in chronic HIV disease.
Wrong parasite, wrong host? How Plasmodium falciparum erythrocyte membrane protein 1 expression and the host’s innate immune response combine to influence the inflammatory response to malaria in vitro and in vivo. Implications for severe malaria
  • 批准号：
    nhmrc : 1061993
  • 项目类别：
    Project Grants
  • 资助金额：
    $47.2万
  • 财政年份：
    2014
  • 负责人：
    A/Pr Anthony Jaworowski
  • 依托单位：
    The University of Melbourne
A longitudinal study of Natural Killer cell function in HIV-infected individuals initiating therapy
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