Wrong parasite, wrong host? How Plasmodium falciparum erythrocyte membrane protein 1 expression and the host’s innate immune response combine to influence the inflammatory response to malaria in vitro and in vivo. Implications for severe malaria

错误的寄生虫，错误的宿主？

• 批准号: nhmrc : 1061993
• 负责人: A/Pr Anthony Jaworowski
• 金额: $ 47.2万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/wrong-parasite-wrong-severe-malaria/454951
• 关键词: Wrong; parasite; wrong; host; How

One factor that determines whether some children die of malaria is the type of protein that the parasite expresses on the red blood cell, to help it stick in blood vessels. Our new data suggests that some proteins stimulate excessive host immune response,

决定一些儿童是否死于疟疾的一个因素是寄生虫在红细胞上表达的蛋白质类型，以帮助它粘在血管中。我们的新数据表明，一些蛋白质刺激过度的宿主免疫反应，