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Phagocytic clearance and immune activation in malaria

Phagocytic clearance and immune activation in malaria
疟疾中的吞噬细胞清除和免疫激活
批准号:
nhmrc : 628611
负责人:
A/Pr Anthony Jaworowski
金额:
$37.65万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31

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中文摘要
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英文摘要
Macrophage white blood cells clear malaria infected cells by eating them, by three routes- by recognising ANTIBODIES or COMPLEMENT on the cell surface, or by the cell BINDING directly to the macrophage. Each has different results, such as amounts of cytokines produced. Cytokines clear malaria; in excess they can cause fatal immune pathology. We will investigate how variations in amount of antibody and complement and route of uptake of malaria infected cells might determine malaria outcome.
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会议论文
A new monocyte atherogenic phenotype in chronic HIV disease.
  • 批准号:
    nhmrc : GNT1108792
  • 项目类别:
    Project Grants
  • 资助金额:
    $63.2万
  • 财政年份:
    2016
  • 负责人:
    A/Pr Anthony Jaworowski
  • 依托单位:
A new monocyte atherogenic phenotype in chronic HIV disease.
A longitudinal study of Natural Killer cell function in HIV-infected individuals initiating therapy
国内基金
海外基金
内质网–质膜互作在凋亡细胞磷脂酰丝氨酸外翻过程中的作用机制研究
  • 批准号:
    91954114
  • 项目类别:
    重大研究计划
  • 资助金额:
    76.0万元
  • 批准年份:
    2019
  • 负责人:
    肖辉
  • 依托单位: