A Compact and Durable Catheter Pump

紧凑耐用的导管泵

• 批准号: 6337239
• 负责人: HSIANG M CHEN
• 金额: $ 19.66万
• 依托单位: FOSTER-MILLER TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2002-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6337239
• 关键词: bioengineering /biomedical engineering; biomaterial compatibility; biomechanics; biomedical equipment development; catheterization; circulatory assist; extracorporeal circulation; mechanical pressure; surgery material /equipment; temperature

DESCRIPTION (Verbatim from the Applicant's Abstract): A small, intravascular catheter pump providing adequate output, good blood compatibility, and high reliability is being designed for use as a cardiac-assist pump in the operating room or interventional cardiology laboratory. This pump would function not only for minimally invasive surgery, but also as a valuable, intermediate level of support between balloon pumps and the much more invasive cardiopulmonary bypass or ventricle-assist devices. Compared to existing catheter pumps, the proposed design is unique in its use of magnetic bearings, and, thus, avoids mechanical bearings or seals that could cause thrombosis. Further, since blood flows through the motor gap, as well as over the outside diameter, the motor is well-cooled, allowing for the compactness of the design and the mechanical durability (i.e., high reliability) of the pump over extended periods. The Phase I pump is 7 mm in diameter, and designed to produce 3 I/min at 90 mm Hg when running at approximately 30,000 rpm. During Phase I, test data will be used to optimize the design at or below 6-mm outside diameter to enhance the pump's potential for peripheral, as well as central, insertion in the aorta. During Phase II, a production prototype will be designed, bench-tested, and in-vivo tested. PROPOSED COMMERCIAL APPLICATION: The market for the proposed catheter pump evolves from the cardiac, minimally invasive surgery field, which is estimated to include over 30,000 cases in 2000, and is still be growing rapidly. The pump will also be a more hemodynamically potent cardiac-assist device than balloon pump, which are predicted to have sales of nearly 90,000 units in 2000.

描述（逐字摘自申请人的摘要）：小型血管内 导管泵提供足够的输出、良好的血液相容性和高 可靠性被设计为在手术中用作心脏辅助泵 室或介入心脏病学实验室。该泵不仅可以发挥作用 用于微创手术，也可作为有价值的中级手术 球囊泵和更具侵入性的心肺旁路之间的支持 或心室辅助装置。与现有的导管泵相比，建议 设计的独特之处在于它使用磁力轴承，因此避免了机械 可能导致血栓形成的轴承或密封件。此外，由于血液流动 通过电机间隙以及外径，电机 冷却良好，考虑到设计和机械的紧凑性 泵的长期耐用性（即高可靠性）。这 第一阶段泵的直径为 7 毫米，设计为在 90 毫米汞柱下产生 3 I/min 当以大约 30,000 rpm 的速度运行时。在第一阶段，测试数据将 用于优化外径 6 毫米或以下的设计，以增强 泵在主动脉周围和中央插入的潜力。 在第二阶段，将设计生产原型、进行台架测试并 体内测试。 拟议的商业应用： 拟议的导管泵市场从心脏、微创 2000 年估计有超过 30,000 例手术领域，并且仍处于 快速增长。 该泵还将成为血流动力学更有效的心脏辅助装置 比气球泵更重要的设备，预计在 2020 年销量将接近 90,000 台 2000年。