A Compact and Durable Catheter Pump

紧凑耐用的导管泵

• 批准号: 6337239
• 负责人: HSIANG M CHEN
• 金额: $ 19.66万
• 依托单位: FOSTER-MILLER TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2002-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6337239
• 关键词: bioengineering /biomedical engineering; biomaterial compatibility; biomechanics; biomedical equipment development; catheterization; circulatory assist; extracorporeal circulation; mechanical pressure; surgery material /equipment; temperature

DESCRIPTION (Verbatim from the Applicant's Abstract): A small, intravascular catheter pump providing adequate output, good blood compatibility, and high reliability is being designed for use as a cardiac-assist pump in the operating room or interventional cardiology laboratory. This pump would function not only for minimally invasive surgery, but also as a valuable, intermediate level of support between balloon pumps and the much more invasive cardiopulmonary bypass or ventricle-assist devices. Compared to existing catheter pumps, the proposed design is unique in its use of magnetic bearings, and, thus, avoids mechanical bearings or seals that could cause thrombosis. Further, since blood flows through the motor gap, as well as over the outside diameter, the motor is well-cooled, allowing for the compactness of the design and the mechanical durability (i.e., high reliability) of the pump over extended periods. The Phase I pump is 7 mm in diameter, and designed to produce 3 I/min at 90 mm Hg when running at approximately 30,000 rpm. During Phase I, test data will be used to optimize the design at or below 6-mm outside diameter to enhance the pump's potential for peripheral, as well as central, insertion in the aorta. During Phase II, a production prototype will be designed, bench-tested, and in-vivo tested. PROPOSED COMMERCIAL APPLICATION: The market for the proposed catheter pump evolves from the cardiac, minimally invasive surgery field, which is estimated to include over 30,000 cases in 2000, and is still be growing rapidly. The pump will also be a more hemodynamically potent cardiac-assist device than balloon pump, which are predicted to have sales of nearly 90,000 units in 2000.

描述（来自申请人摘要的逐字描述）：一种小的血管内 导管泵提供足够的输出，良好的血液相容性， 可靠性被设计用于心脏辅助泵的操作， 室或介入心脏病学实验室。这台泵不仅可以 对于微创手术，但也作为一个有价值的，中间水平的 球囊泵和更具侵入性的心肺转流之间的支持 或心室辅助装置。与现有的导管泵相比， 设计是独特的，在其使用的磁性轴承，并因此，避免了机械 可能导致血栓形成的轴承或密封件。此外，由于血液流动 通过电机间隙以及外径，电机 良好的冷却，考虑到设计的紧凑性和机械性能 耐久性（即，高可靠性）。的 第一阶段泵的直径为7 mm，设计为在90 mm Hg下产生3 I/min 当以大约30，000 rpm运行时。在第一阶段，测试数据将 用于优化外径等于或小于6 mm的设计， 泵的潜力，以及中央，插入主动脉。 在第二阶段，将设计生产原型，进行台架测试， 体内测试。 拟定商业应用： 拟议的导管泵市场从心脏微创泵发展到 外科领域，估计2000年包括30 000多个病例， 生长迅速。 该泵也将是一个更强大的血液动力学心脏辅助 设备比球囊泵，预计将有近90,000单位的销售， 2000.