Low-Cost Rotary Blood Pump with ICB Magnetic Support

带 ICB 磁力支撑的低成本旋转式血泵

• 批准号: 6689892
• 负责人: HSIANG M CHEN
• 金额: $ 30.4万
• 依托单位: FOSTER-MILLER TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-10 至 2005-07-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6689892
• 关键词: auxiliary heart prosthesis; bioengineering /biomedical engineering; biomedical equipment development; circulatory assist; clinical biomedical equipment

DESCRIPTION (provided by applicant): An "Inherently Controlled Bearing" (ICB) concept has been demonstrated in a magnetically suspended rotary blood pump intended for use as a permanently implanted ventricular assist device (VAD). The ICB eliminates not only position sensors but also active feedback electronic control of the bearing coil currents, and good efficiency and high stiffness of a prototype ICB has been documented. The specific aim of this Fast-Track proposal is to demonstrate that this innovative technology can be extended to produce a very low cost, yet highly durable, pump for medium-term uses, such as extracorporeal lung support (ECLS), or bridge-to-transplant/recovery use. To accomplish this, several additional innovations will be incorporated in the pump design. Walls between the rotor and stator housings will be introduced to isolate the blood path from the now separable and reusable stators. The motor will be redesigned to provide the speed and power required for the wider range of hydraulic output, and the rotor diameter decreased, reducing viscous drag losses by more than the resulting speed increase and reducing the motor torque output required for a particular hydraulic output. Lower cost materials and manufacturing methods will be incorporated to fabricate this nonpermanent, nonimplanted pump. Success in Phase I will be a prototype with sufficient stiffness in the bearing to resist all imposed shock and vibration loads and a bearing power consumption below 2.5 W, at all operating conditions. The prototype will also demonstrate an ability to pump 5 liter/min at 100 mm-Hg pressure rise with motor power input below 8 W, an ability to pump 4 liter/min at 350 mm-Hg pressure rise with motor power below 25 W, and an ability to pump 9 liter/min at 120 mm-Hg pressure rise, with 40 W maximum power. The advantage of success here is that a common, core technology will become available for blood pump applications. Cost benefits will accrue from this commonality, and in quantities of 1000 or more per year, the simple disposable element can be sold at a price competitive with existing products. Improvements on rates of thrombus formation and bearing durability will also be realized, and the relatively small size would allow use as a wearable bridge-to-transplant/recovery device, it would also offer an alternative for small patients, for transient right ventricle support after LVAD implant, or for marketplaces that cannot afford implantable pump costs.

描述（由申请人提供）： 在预期用作永久植入式心室辅助装置（VAD）的磁悬浮旋转血泵中，已经证明了“固有控制轴承”（ICB）概念。ICB不仅消除了位置传感器，而且消除了轴承线圈电流的主动反馈电子控制，并且已经记录了原型ICB的良好效率和高刚度。本快速通道提案的具体目的是证明这种创新技术可以扩展到生产一种成本非常低但非常耐用的泵，用于中期用途，例如体外肺支持（ECLS）或移植/恢复桥接用途。为了实现这一目标，将在泵设计中加入几项额外的创新。转子和定子外壳之间的壁将被引入，以将血液路径与现在可分离和可重复使用的定子隔离。马达将重新设计，以提供更宽范围的液压输出所需的速度和功率，并且转子直径减小，从而减少粘性阻力损失超过由此产生的速度增加，并减少特定液压输出所需的马达扭矩输出。低成本的材料和制造方法将被纳入制造这种非永久性的，非植入泵。在第一阶段的成功将是一个原型有足够的刚度在轴承抵抗所有强加的冲击和振动载荷和轴承功耗低于2.5 W，在所有操作条件。该原型还将展示在100 mm Hg压力升高下以低于8 W的电机功率输入泵送5升/分钟的能力，在350 mm Hg压力升高下以低于25 W的电机功率泵送4升/分钟的能力，以及在120 mm Hg压力升高下以40 W最大功率泵送9升/分钟的能力。成功的优势在于，一种通用的核心技术将可用于血泵应用。成本效益将从这种通用性中产生，并且以每年1000个或更多的数量，简单的一次性元件可以以与现有产品竞争的价格出售。还将实现血栓形成率和轴承耐久性的改善，并且相对较小的尺寸将允许用作可穿戴的移植/恢复桥接装置，它还将为小型患者提供替代方案，用于LVAD植入后的短暂右心室支持，或用于无法负担植入式泵成本的市场。