TRAINING PROGRAM IN INVESTIGATIVE GASTROENTEROLOGY

描述（改编自应用程序） 这个新的胃肠病学研究培训计划的目标是准备 医学博士，哲学博士、或医学博士/博士博士后研究员作为独立的职业 学术胃肠病学的研究者。多元化和经验丰富的教师 将提供学习当代细胞方法的机会， 分子生物学或临床研究的导师在四个广泛的 领域：A）损伤，纤维化和信号传导; B）癌症生物学和免疫学; C） 转运和基因治疗的分子基础;或D）基于专利的临床 肝胆胃肠道疾病调查。培训将 为今后在调查方面取得成功奠定坚实基础 胃肠病学。为此，已从 消化科、肝病科、心脏科及其他 临床和基础科学部门和中心内的学校 医学（儿科学系;生物化学，发展和 免疫生物学中心卫生政策系分子生物学 基因治疗和分子医学研究所;以及鲁滕贝格癌症研究所 中）。学员将从四个来源之一进入这个程序：1）MD或 完成18个月至2年成人临床培训的MD/PhD 胃肠病学，2）医学博士或医学博士/博士谁已经完成了1-2年的 胃肠病学奖学金加一年临床肝病学奖学金; 3） 已完成1年临床儿科学的MD或MD/PhD 胃肠病学奖学金; 4）完成博士学位的博士生 在生命科学的计划。培训生候选人将致力于 至少三年的实验室或患者培训 research.每年该补助金将支持4名学员：1-2名在PGY的学员 5级，1-2个在PGY 6级，1个在PGY 7级。至少90%的学员 时间将用于在实验室或医院环境中工作， 一个或多个指导下的具体，个性化的研究项目 教师导师此外，所有学员将参加每周一次的 实验室或临床小组会议，参加相关部门、部门 和机构研究为导向的会议，并将报名参加 专门设计的实验室或临床研究课程 方法.这一强调转化研究的综合提案出现了 从一个充满活力，快速发展的学术机构，一个已经创造了一个 为优秀的临床医生和生物医学实习生提供理想的环境 阐明和治疗胃肠道疾病。

DESCRIPTION (adapted from the application) The goal of this new Gastroenterology Research Training Program is to prepare M.D., Ph.D., or M.D./Ph.D. postdoctoral fellows for careers as independent investigators in academic Gastroenterology. A diverse and experienced faculty will provide the opportunity to learn contemporary methods of cellular and molecular biology or clinical research by mentorship in one of four broad areas: A) Injury, Fibrosis & Signaling; B) Cancer Biology & Immunology; C) Molecular Basis of Transport & Gene Therapy; or D) Patent‑based Clinical Investigation in Hepatobiliary and Gastrointestinal Diseases. The training will provide a solid foundation for future success in investigative Gastroenterology. To do so, expert faculty have been recruited from the Divisions of Gastroenterology, Liver Diseases, and Cardiology, and other Clinical and Basic Science Departments and Centers within the School of Medicine (the Dept of Pediatrics; Dept of Biochemistry, Developmental & Molecular Biology; Dept of Health Policy; the Immunobiology Center; the Institute for Gene Therapy and Molecular Medicine; and the Ruttenberg Cancer Center). Trainees will enter this program from one of four sources: 1) MDs or MD/PhDs who have completed 18 months to 2 years of training in adult clinical Gastroenterology, 2) MDs or MD/PhDs who have completed 1-2 years of Gastroenterology fellowship plus a year of clinical Hepatology fellowship; 3) MDs or MD/PhDs who have completed 1 year of a clinical Pediatric Gastroenterology fellowship; 4) PhD trainees who have completed a doctoral program in life sciences. Trainee candidates will be expected to devote a minimum of three years to training in either laboratory- or patient-based research. Each year this grant will support 4 trainees: 1-2 trainees at the PGY 5 level, 1-2 at the PGY 6 and one at the PGY 7 level. At least 90% of trainees time will be devoted to working in the laboratory or hospital setting on a specific, individualized research project under the guidance of one or more faculty mentors. In addition, all trainees will participate in weekly laboratory or clinical group meetings, attend relevant divisional, departmental and institutional research‑oriented conferences, and will enroll in specifically designed coursework in laboratory or clinical investigative methods. This integrated proposal emphasizing translational research emerges from a dynamic, rapidly growing academic institution, one that has created an ideal environment for equipping outstanding clinicians and biomedical trainees to elucidate and treat gastrointestinal diseases.