课题基金 / 基金详情

PET STUDY OF CNS BENZODIAZEPINE RECEPTORS IN ADOLESCENT ONSET ALCOHOLISM

PET STUDY OF CNS BENZODIAZEPINE RECEPTORS IN ADOLESCENT ONSET ALCOHOLISM
青少年酒精中毒中枢神经系统苯二氮卓受体的 PET 研究
批准号：
6304692
负责人：
DUNCAN B. CLARK
金额：
$0.3万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6304692
关键词：
adolescence (12-20) alcoholic beverage consumption alcoholism /alcohol abuse benzodiazepine receptor central nervous system disorders clinical research human subject neurochemistry positron emission tomography receptor expression receptor sensitivity toxicant interaction toxicology

项目摘要

项目成果

DUNCAN B. CLARK的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This study proposes to obtain pilot data on the effects of chronic and alcohol consumption on benzodiazepine receptor (BZR) distribution and density in adolescent onset alcohol dependence using [11C] flumazenil binding visualized by PET. Alterations in the gamma-aminobutyric acid (GABA) neurotransmitter system induced by chronic alcohol consumption represent the mostly likely neurochemical substrate of alcohol dependence. Subjects with adolescent-onset alcohol use disorders, compared with controls, will show reduced binding of [11C]-flumazenil in the cingulate cortex.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Phenotyping and Biobanking Core
Phenotyping and Biobanking Core
Phenotyping and Biobanking Core
12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGH
海外基金