Parallel Array Processor

并行阵列处理器

• 批准号: 6484978
• 负责人: MARK S. CHEE
• 金额: $ 55.88万
• 依托单位: ILLUMINA, INC.
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-23 至 2004-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6484978
• 关键词: biomedical automation; biomedical equipment development; cell line; clinical research; complementary DNA; computer system design /evaluation; fiber optics; fluorescent dye /probe; genotype; high throughput technology; messenger RNA; microarray technology; nucleic acid hybridization; nucleic acid purification; oligonucleotides; parallel processing; robotics; single nucleotide polymorphism

DESCRIPTION (provided by applicant): Microarrays are designed to allow many experiments to be carried out simultaneously on a single sample, and are highly efficient in this regard. However, commercially available microarray technologies are not designed for the analysis of large numbers of samples, and are costly and cumbersome to apply in this way. There is an increasing need for an array technology that will permit many samples to be processed efficiently, accurately, cost-effectively, and reproducibly. We have developed an array technology with these requirements in mind. This project aims to develop further a system for parallel processing of arrays. The system is based on a matrix of arrays in a microtiter format, and aims to provide researchers with a capability for large-scale analysis of complex genetic systems that is currently attainable only in costly large-scale production environments. It will allow researchers to carry out array-based SNP genotyping and RNA profiling experiments on thousands of samples per day. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述（由申请人提供）：微阵列的设计允许许多 实验同时进行一个单一的样品，并高度 在这方面有效率。然而，市售微阵列 技术不是为分析大量样品而设计的， 以这种方式应用是昂贵和麻烦的。越来越需要 一种允许有效处理许多样品的阵列技术， 准确、经济、可重复。我们开发了一个阵列 技术，满足这些要求。该项目旨在开发 还涉及一种用于阵列的并行处理的系统。该系统基于一个 矩阵的阵列在微量滴定格式，并旨在为研究人员提供一个 大规模分析复杂遗传系统的能力， 目前只能在昂贵的大规模生产环境中实现。它 将允许研究人员进行基于阵列的SNP基因分型和RNA 每天对数千个样本进行分析实验。 拟议商业应用：不可用