RESEARCH TRAINING IN PHYSIOLOGICAL ADAPTATION TO STRESS

压力生理适应研究培训

• 批准号: 6498492
• 负责人: PETER A FARRELL
• 金额: $ 17.05万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6498492
• 关键词: RESEARCH; TRAINING; PHYSIOLOGICAL; ADAPTATION; STRESS

DESCRIPTION: (provided by applicant) The predoctoral training program entitled "Research Training in Physiological Adaptations to Stress" during its first funding period, has attracted excellent students and the five graduates of the program have obtained first rate postdoctoral positions or positions in industry. Sixty percent of the NIH funded slots are currently filled with minority students. Based on this success, we seek continued support of the program for another five years. Physiological adaptations to stress encompass a wide range of responses from alterations of molecular structure affecting cellular metabolism to organismal remodeling. Adaptations may be positive, such as those brought about by increased participation in regular physical activity, or they may have pathological sequelae such as hypermetabolic responses to trauma. Our predoctoral training program takes advantage of the existing, internationally recognized strengths of faculty located at the College of Medicine at the Hershey Campus and within several departments at the University Park campus of The Pennsylvania State University. The goal of the ongoing training program is to develop scientists with an ability to generate, integrate, and apply knowledge gathered by multiple approaches to the study of stress physiology. The training program will continue to be housed in the Intercollege Graduate Program in Physiology, which has a thirty-five year history of interdisciplinary graduate student education. Faculty members of the training program are committed to enhancing diversity through minority recruitment and to promoting ethics in research. The training program seeks support for 8 predoctoral trainees per year whose proficiency to integrate information gathered at many levels of inquiry will be developed by a rigorous curriculum, structured research experiences and dedicated mentorship. A core course has been developed specifically for this program, "Physiological Adaptations to Stress and continues to serve as an early introduction to the goals of this training program. A rich academic environment is provided at both campuses with strong research support and institutional commitment. The Pennsylvania State University will continue to provide four full assistantships as a match for this training grant. Students who complete their training through this program will not only have a thorough knowledge of laboratory techniques ranging from molecular to whole organism, but they will also have the capacity to understand and synthesize complex information resulting from research examining the physiological adaptations to stress.

产品说明：（申请人提供）博士前培训项目“压力生理适应研究培训”在第一个资助期内吸引了优秀学生，该项目的五名毕业生获得了一流的博士后职位或行业职位。目前，NIH资助的60%的名额都是少数民族学生。基于这一成功，我们寻求在未来五年内继续支持该计划。对压力的生理适应包括从影响细胞代谢的分子结构改变到生物体重塑的广泛范围的反应。适应可能是积极的，例如增加参与定期体力活动所带来的适应，或者它们可能有病理后遗症，例如对创伤的高代谢反应。我们的博士前培训计划利用了位于好时校区医学院和宾夕法尼亚州立大学大学公园校区几个部门内的现有国际公认的教师优势。正在进行的培训计划的目标是培养具有生成，整合和应用通过多种方法收集的知识来研究压力生理学的能力的科学家。该培训计划将继续被安置在跨学院研究生课程生理学，其中有35年的跨学科研究生教育的历史。培训计划的教师致力于通过少数民族招聘和促进研究道德提高多样性。该培训计划每年寻求8名博士前学员的支持，他们整合在多个层次调查收集的信息的能力将通过严格的课程，结构化的研究经验和专门的导师来开发。一个核心课程已经开发了专门为这个程序，“生理适应压力，并继续作为一个早期介绍这个培训计划的目标。两个校区都提供了丰富的学术环境，并提供了强大的研究支持和机构承诺。宾夕法尼亚州立大学将继续提供四个全额助学金，以配合这一培训赠款。通过该计划完成培训的学生不仅将全面了解从分子到整个生物体的实验室技术，而且他们还将有能力理解和综合研究压力生理适应性所产生的复杂信息。