Elucidating the pathogenic role of rotavirus infection in type 1 diabetes development
Elucidating the pathogenic role of rotavirus infection in type 1 diabetes development
批准号:
nhmrc : 1044868
负责人:
A/Pr Barbara Coulson
金额:
$35.71万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
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英文摘要
Rotavirus infection is the main cause of severe diarrhoea in children, and has been implicated in accelerated progression of genetically at-risk children towards type 1 diabetes in two independent studies. My group has further discovered that rotavirus also accelerates diabetes onset in mice in a novel immunological process. In this project, we will determine the mechanism behind this disease exacerbation in the mice, to facilitate understanding of the process in children.
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会议论文
Understanding how virus infection accelerates type 1 diabetes development
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批准号:nhmrc : 1103279
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项目类别:Project Grants
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资助金额:$41.88万
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财政年份:2016
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负责人:A/Pr Barbara Coulson
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依托单位:
Understanding how virus infection accelerates type 1 diabetes development
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批准号:nhmrc : GNT1103279
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项目类别:Project Grants
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资助金额:$61.08万
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财政年份:2016
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负责人:A/Pr Barbara Coulson
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依托单位:
NEW INSIGHT INTO GLYCAN REQUIREMENTS FOR ROTAVIRUS-CELL ATTACHMENT AND ENTRY
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批准号:nhmrc : GNT1085596
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项目类别:Project Grants
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资助金额:$103.05万
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财政年份:2015
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负责人:A/Pr Barbara Coulson
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依托单位:
NEW INSIGHT INTO GLYCAN REQUIREMENTS FOR ROTAVIRUS-CELL ATTACHMENT AND ENTRY
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批准号:nhmrc : 1085596
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项目类别:Project Grants
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资助金额:$71.26万
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财政年份:2015
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负责人:A/Pr Barbara Coulson
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依托单位:
Innate immune responses to rotavirus infection
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批准号:nhmrc : 1023786
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项目类别:Project Grants
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资助金额:$35.62万
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财政年份:2012
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负责人:A/Pr Barbara Coulson
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依托单位:
Research Fellowship
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批准号:nhmrc : 628319
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项目类别:NHMRC Research Fellowships
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资助金额:$47.72万
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财政年份:2010
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负责人:A/Pr Barbara Coulson
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依托单位:
Glycan specificity and dependence in rotavirus host cell invasion
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批准号:nhmrc : 597439
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项目类别:NHMRC Project Grants
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资助金额:$42.45万
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财政年份:2010
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负责人:A/Pr Barbara Coulson
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依托单位:
Modulation of type 1 diabetes development by rotavirus infection
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批准号:nhmrc : 509008
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项目类别:NHMRC Project Grants
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资助金额:$27.59万
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财政年份:2008
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负责人:A/Pr Barbara Coulson
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依托单位:
Immune cell interactions and cell signalling pathways important for rotavirus infection
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批准号:nhmrc : 509006
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项目类别:NHMRC Project Grants
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资助金额:$22.93万
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财政年份:2008
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负责人:A/Pr Barbara Coulson
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依托单位:
Roles of virus-integrin interactions and rotavirus modulation of host cell responses in viral pathogenesis
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批准号:nhmrc : 350252
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项目类别:NHMRC Project Grants
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资助金额:$31.61万
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财政年份:2005
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负责人:A/Pr Barbara Coulson
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依托单位:
Research Fellowship - Grant ID:350253
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批准号:nhmrc : 350253
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项目类别:NHMRC Research Fellowships
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资助金额:$35.89万
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财政年份:2005
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负责人:A/Pr Barbara Coulson
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依托单位:
Analysis of the role of rotavirus infection in development of type 1 diabetes
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批准号:nhmrc : 299862
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项目类别:NHMRC Project Grants
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资助金额:$23.26万
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财政年份:2004
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负责人:A/Pr Barbara Coulson
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依托单位:
Oxidised mannan as a novel adjuvant to vaccinate against mucosal infections
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批准号:nhmrc : 223324
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项目类别:NHMRC Development Grants
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资助金额:$10.0万
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财政年份:2003
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负责人:A/Pr Barbara Coulson
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依托单位:
Roles of integrins in rotavirus cell attachment, entry and tropism
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批准号:nhmrc : 208900
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项目类别:NHMRC Project Grants
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资助金额:$22.64万
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财政年份:2002
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负责人:A/Pr Barbara Coulson
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依托单位:
Ongoing uncoupled research fellowship
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批准号:nhmrc : 172305
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项目类别:NHMRC Research Fellowships
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资助金额:$27.15万
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财政年份:2001
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负责人:A/Pr Barbara Coulson
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依托单位:
Cellular and viral components involved in rotavirus entry into cells
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批准号:nhmrc : 980635
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项目类别:NHMRC Project Grants
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资助金额:$33.64万
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财政年份:1998
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负责人:A/Pr Barbara Coulson
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依托单位:
国内基金
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Erk1/2/CREB/BDNF通路在CSF1R相关性白质脑病致病机制中的作用研究
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批准号:82371255
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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依托单位:
CD8+T细胞亚群在抗MDA5抗体阳性皮肌炎中的致病机制研究
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项目类别:面上项目
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资助金额:45.00万元
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批准年份:2023
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负责人:扶琼
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依托单位:
新生儿坏死性小肠结肠炎中去泛素化酶USP15调控ILC3分化损伤肠道粘膜屏障的致病机制研究
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批准号:82371711
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:吕志宝
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依托单位: