Glycan specificity and dependence in rotavirus host cell invasion
Glycan specificity and dependence in rotavirus host cell invasion
批准号:
nhmrc : 597439
负责人:
A/Pr Barbara Coulson
金额:
$42.45万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
轮状病毒是一种全球性病原体,可引起急性胃肠炎,导致脱水和高水平的婴儿死亡率。每年,感染导致1.38亿婴儿胃肠炎病例,估计平均死亡60万人。在澳大利亚,每年约有10,000名5岁以下儿童因轮状病毒引起的严重腹泻入院。该项目将研究碳水化合物在轮状病毒感染中的作用,以帮助设计新的疫苗和抑制剂。
英文摘要
Rotavirus is a global pathogen that causes acute gastroenteritis resulting in dehydration and high levels of infant mortality. Annually, infections cause 138 million cases of infantile gastroenteritis and an estimated average of 600,000 deaths. Within Australia ~10,000 children under 5 yrs old are admitted to hospital annually with severe rotavirus-induced diarrhoea. This project will investigate the role of carbohydrates in rotavirus infection to help design new vaccines and inhibitors.
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会议论文
Understanding how virus infection accelerates type 1 diabetes development
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批准号:nhmrc : 1103279
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项目类别:Project Grants
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资助金额:$41.88万
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财政年份:2016
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负责人:A/Pr Barbara Coulson
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依托单位:
Understanding how virus infection accelerates type 1 diabetes development
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批准号:nhmrc : GNT1103279
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项目类别:Project Grants
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资助金额:$61.08万
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财政年份:2016
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负责人:A/Pr Barbara Coulson
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依托单位:
NEW INSIGHT INTO GLYCAN REQUIREMENTS FOR ROTAVIRUS-CELL ATTACHMENT AND ENTRY
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批准号:nhmrc : GNT1085596
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项目类别:Project Grants
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资助金额:$103.05万
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财政年份:2015
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负责人:A/Pr Barbara Coulson
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依托单位:
NEW INSIGHT INTO GLYCAN REQUIREMENTS FOR ROTAVIRUS-CELL ATTACHMENT AND ENTRY
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批准号:nhmrc : 1085596
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项目类别:Project Grants
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资助金额:$71.26万
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财政年份:2015
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负责人:A/Pr Barbara Coulson
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依托单位:
Elucidating the pathogenic role of rotavirus infection in type 1 diabetes development
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批准号:nhmrc : 1044868
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资助金额:$35.71万
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财政年份:2013
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依托单位:
Innate immune responses to rotavirus infection
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批准号:nhmrc : 1023786
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财政年份:2012
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负责人:A/Pr Barbara Coulson
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依托单位:
Research Fellowship
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批准号:nhmrc : 628319
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项目类别:NHMRC Research Fellowships
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资助金额:$47.72万
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财政年份:2010
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负责人:A/Pr Barbara Coulson
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依托单位:
Modulation of type 1 diabetes development by rotavirus infection
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批准号:nhmrc : 509008
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项目类别:NHMRC Project Grants
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财政年份:2008
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依托单位:
Immune cell interactions and cell signalling pathways important for rotavirus infection
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项目类别:NHMRC Project Grants
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资助金额:$22.93万
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财政年份:2008
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负责人:A/Pr Barbara Coulson
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依托单位:
Roles of virus-integrin interactions and rotavirus modulation of host cell responses in viral pathogenesis
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批准号:nhmrc : 350252
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财政年份:2005
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负责人:A/Pr Barbara Coulson
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依托单位:
Research Fellowship - Grant ID:350253
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批准号:nhmrc : 350253
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项目类别:NHMRC Research Fellowships
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资助金额:$35.89万
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财政年份:2005
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负责人:A/Pr Barbara Coulson
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依托单位:
Analysis of the role of rotavirus infection in development of type 1 diabetes
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批准号:nhmrc : 299862
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项目类别:NHMRC Project Grants
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资助金额:$23.26万
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财政年份:2004
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负责人:A/Pr Barbara Coulson
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依托单位:
Oxidised mannan as a novel adjuvant to vaccinate against mucosal infections
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批准号:nhmrc : 223324
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项目类别:NHMRC Development Grants
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资助金额:$10.0万
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财政年份:2003
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负责人:A/Pr Barbara Coulson
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依托单位:
Roles of integrins in rotavirus cell attachment, entry and tropism
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批准号:nhmrc : 208900
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项目类别:NHMRC Project Grants
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资助金额:$22.64万
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财政年份:2002
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负责人:A/Pr Barbara Coulson
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依托单位:
Ongoing uncoupled research fellowship
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批准号:nhmrc : 172305
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项目类别:NHMRC Research Fellowships
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资助金额:$27.15万
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财政年份:2001
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负责人:A/Pr Barbara Coulson
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依托单位:
Cellular and viral components involved in rotavirus entry into cells
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批准号:nhmrc : 980635
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项目类别:NHMRC Project Grants
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资助金额:$33.64万
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财政年份:1998
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负责人:A/Pr Barbara Coulson
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依托单位:
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