Race Differences in Female UI: Epidemiology and Biology

描述(申请人提供)：尿失禁患病率为 经常有报道称，黑人女性的这一比例低于白人女性。不管是不是 这是真的，在基于人群的年轻研究中尚未得到证实 女人。此外，造成这一患病率差异的原因还包括 未知。这项拟议的基于人群的横断面研究将测试 认为尿路感染总体患病率无差异的无效假设 黑人和白人女性大小便失禁。关于以下问题的电话调查 尿失禁(UT)的发生及其可能相关因素 UT将在1000名白人女性和1500名白人女性的地区样本中进行 黑人女性年龄在30-60岁之间。130个黑白重音的子样本 尿失禁，100个黑白催眠和100个黑白 白人大陆妇女将接受骨盆形式的临床测试 地面测试以量化膀胱和尿路功能。这项调查将 实现以下目标：目标a：确定尿路疾病的患病率 黑人和白人女性大小便失禁。目标1B：确定 对黑人和白人女性施加压力并敦促她们大小便失禁。目标2：确定 可能解释患病率差异的人口和个人因素 在两场比赛之间。临床试验将达到以下目的。目标 3：比较黑人和白人女性和女性的尿路和盆底功能 大小便失禁的女性。调查和临床部分相结合 才能达到最终目的。目标4：确定流行病学和临床 与尿失禁相关的因素。这项研究将证实 报告的尿失禁患病率存在种族差异。会的 还要确定哪些流行病学和临床因素对此有影响 不同。对这些因素的了解可以为风险提供基础 确定因素并制定适当的预防策略 不同的种族群体。

DESCRIPTION (provided by applicant): The prevalence of urinary incontinence is often reported to be lower in black women than in white women. Whether or not this is true has not been confirmed in population based studies of younger women. In addition, the reasons for this prevalence difference are also unknown. This proposed population based, cross-sectional study will test the null hypothesis that no difference exists in the overall prevalence of urinary incontinence in black and white women. A telephone survey concerning occurrence of urinary incontinence (UT) and factors possible associated with UT will be administered to a regional sample of 1000 white women and 1500 black women age 30-60 years. A sub-sample of 130 black and white stress urinary incontinent, 100 black and white urge incontinent and 100 black and white continent women will undergo clinical testing in the form of pelvic floor testing to quantify bladder and urethra function. This survey will achieve the following aims: Aim lA: Define the prevalence of urinary incontinence in black and white women. Aim 1B: Determine the prevalence of stress and urge incontinence in black and white women. Aim 2: Identify demographic and personal factors that might explain the prevalence differences between the races. The clinical testing will accomplish the following aim. Aim 3: Compare the urethral and pelvic floor function of black and white women and continent and incontinent women. The survey and clinical components combined will achieve the final aim. Aim 4: Identify both epidemiologic and clinical factors associated with urinary incontinence. This research will confirm the reported race differences in the prevalence of urinary incontinence. It will also identify which epidemiologic and clinical factors contribute to this difference. Knowledge of these factors can then provide the basis for risk factor identification and the development of preventive strategies appropriate to different racial groups.