The Epidemiology of Fecal Incontinence after Childbirth

大便失禁被认为是一种具有深远社会影响的常见疾病。产科分娩被认为是导致女性尿失禁的主要原因。没有基于人群的分娩后大便失禁的研究；风险最高的时期。先前关于产后大便失禁的研究来自单一机构，受转诊偏倚影响的人群，数量较少；使结果无法推广。本建议的主要目标是提供基于人群的发病率和危险因素的信息，这些信息与解剖/生理结果和纵向随访具有重要的相关性。本提案的具体目的是：-提供俄勒冈州所有产后妇女大便失禁发生率的基于人群的估计。-确定产后大便失禁的可改变和不可改变的危险因素。-深入探讨产科分娩方式与产后大便失禁之间可能的因果关系。-建立一个产后大便失禁妇女队列，进行纵向跟踪，以确定预测症状缓解、复发或恶化可能性的因素。-将解剖和生理结果与大便失禁的症状联系起来。-了解大便失禁的生理、心理和社会后果。这些数据将更好地了解问题的严重程度，并将为今后预防和治疗大便失禁的试验提供必要的数据。

Fecal incontinence is thought to be a common condition with profound social impact. Obstetric delivery is thought to be the leading contributor to development of fecal incontinence in women. There are no population-based studies of fecal incontinence following childbirth; the highest-risk period. Previous studies examining postpartum fecal incontinence are from single institutions, populations that are subject to referral bias, and small numbers; making generalizability of the results impossible. The primary goal of this proposal is to provide population-based information on incidence, and risk factors with essential correlation with anatomic/physiologic findings and longitudinal follow-up. The specific aims of this proposal are to: - Provide population-based estimates of incidence of fecal incontinence in all postpartum women delivering in Oregon state. - Identify contributing modifiable and non-modifiable risk factors for the development of postpartum fecal incontinence. - Explore in depth a possible causal relationship between obstetric delivery methods and postpartum fecal incontinence. - Develop a cohort of women with postpartum fecal incontinence to follow longitudinally to identify factors that predict the likelihood of resolution, recurrence or worsening of symptoms. - Correlate anatomic and physiologic findings to symptoms of fecal incontinence. - Understand the physical, psychological, social ramifications of fecal incontinence. These data will provide a better understanding of the extent of the problem and will provide data essential for future trials of prevention and treatment of fecal incontinence.