Early formation of the preplate establishes the cerebral cortex
Early formation of the preplate establishes the cerebral cortex
批准号:
DP140101499
负责人:
Prof Linda Richards
金额:
$47.45万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-06-24
中文摘要
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英文摘要
The cerebral cortex is arguably the most complex area of the brain due to its ability to process and integrate a wide variety of information in a seamless manner. To understand how this occurs, it is essential to understand how the cerebral cortex is built during embryonic life. The focus of this project is on the formation of the very earliest neurons of the cortex, called preplate neurons. This project aims to: test a new model for preplate development with regards to their origin; their function in formation of the cerebral cortex; and the the molecular mechanisms underlying their development. This work provides a developmental framework for understanding how the cerebral cortex is established.
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依托单位:
国内基金
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