Nuclear Factor One genes regulate multiple aspects of cerebral cortex development

核因子一基因调节大脑皮层发育的多个方面

• 批准号: nhmrc : 569504
• 负责人: Prof Linda Richards
• 金额: $ 35.13万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/nuclear-factor-genes-cortex-development/99181
• 关键词: Nuclear; Factor; genes; regulate; multiple

To function, the brain must be formed correctly during embryonic development. We are investigating the embryonic development of the cerebral cortex, an area involved in high-order cognitive processing. Recently, we discovered that an important group of genes regulates cortical development, making it possible to study the underlying molecular mechanisms. The results will impact the prognosis and treatment of developmental brain disorders.

为了发挥功能，大脑必须在胚胎发育期间正确形成。我们正在研究大脑皮层的胚胎发育，这是一个涉及高阶认知处理的区域。最近，我们发现了一组重要的基因调控皮质发育，这使得研究潜在的分子机制成为可能。研究结果将影响发育性脑障碍的预后和治疗。