MICROWAVE RADIOMETRY AS AN ADJUNCT TO MAMMOGRAPHY

微波辐射测量作为乳房 X 光检查的辅助手段

• 批准号: 6777116
• 负责人: KENNETH L CARR
• 金额: $ 35.23万
• 依托单位: MERIDIAN MEDICAL SYSTEMS, LLC
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6777116
• 关键词: bioimaging /biomedical imaging; biopsy; breast neoplasm /cancer diagnosis; diagnosis design /evaluation; diagnosis quality /standard; female; human subject; mammography; microradiography; patient oriented research; technology /technique development; thermography; women's health

DESCRIPTION (Verbatim from Applicant's Abstract): The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. Earlier studies have shown that microwave radiometric sensing is a promising technique which when combined with mammography, would be useful in reducing noncancerous breast biopsies based on mammographic false positives, thereby improving the positive predictive value (PPV) of mammography. These earlier studies will be expanded to include additional clinical sites, investigative ways in which system performance can be improved, and to provide more detailed pathological information that will assist in discovering the reasons for thermal activity. By gaining a better understanding of the reason for thermal anomalies, we can discover the true capabilities of radiometric or thermal-based sensing. Considering the high cost of unnecessary breast biopsies, both financially and emotionally, a system utilizing thermal information should prove to be of great benefit. PROPOSED COMMERCIAL APPLICATION: The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. The data obtained from this study could lead to the development of improved detection techniques and equipment, based on noninvasive thermal sensing, as an adjunct to mammography.

描述(逐字摘自申请者摘要)：长期目标 本研究旨在利用热疗来改善乳腺癌的治疗。 信息作为乳房X光检查的辅助工具，在以下情况下帮助临床决策 面对可疑的乳房X光检查。 早期的研究表明，微波辐射传感是一种很有前途的技术。 这项技术与乳房X光检查相结合，将有助于减少 基于乳房X光摄影假阳性的非癌性乳腺活检，从而 提高乳房X线摄影的阳性预测值。早些时候的这些 研究将扩大到包括更多的临床地点，调查性的 改进系统性能的方法，并提供更详细的 有助于发现疾病原因的病理信息 热活动。 通过更好地了解热异常的原因，我们可以 了解辐射或基于热的传感的真正功能。 考虑到不必要的乳房活检的高昂成本，无论是在经济上还是在 在情感上，利用热信息的系统应该被证明是很好的 利益。 建议的商业应用： 这项研究的长期目标是改善乳腺癌的治疗。 通过利用热信息作为乳房X光检查的辅助手段来辅助临床 在面对模棱两可的乳房X光检查时做出的决定。从以下来源获得的数据 这项研究可能会导致改进的检测技术和 基于非侵入性热感应的设备，作为乳房X光检查的辅助设备。