MICROWAVE RADIOMETRY AS AN ADJUNCT TO MAMMOGRAPHY

微波辐射测量作为乳房 X 光检查的辅助手段

• 批准号: 6795363
• 负责人: KENNETH L CARR
• 金额: $ 36.07万
• 依托单位: MERIDIAN MEDICAL SYSTEMS, LLC
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6795363
• 关键词: bioimaging /biomedical imaging; biopsy; breast neoplasm /cancer diagnosis; diagnosis design /evaluation; diagnosis quality /standard; female; human subject; mammography; microradiography; patient oriented research; technology /technique development; thermography; women' s health

DESCRIPTION (Verbatim from Applicant's Abstract): The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. Earlier studies have shown that microwave radiometric sensing is a promising technique which when combined with mammography, would be useful in reducing noncancerous breast biopsies based on mammographic false positives, thereby improving the positive predictive value (PPV) of mammography. These earlier studies will be expanded to include additional clinical sites, investigative ways in which system performance can be improved, and to provide more detailed pathological information that will assist in discovering the reasons for thermal activity. By gaining a better understanding of the reason for thermal anomalies, we can discover the true capabilities of radiometric or thermal-based sensing. Considering the high cost of unnecessary breast biopsies, both financially and emotionally, a system utilizing thermal information should prove to be of great benefit. PROPOSED COMMERCIAL APPLICATION: The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. The data obtained from this study could lead to the development of improved detection techniques and equipment, based on noninvasive thermal sensing, as an adjunct to mammography.

描述（来自申请人摘要的逐字逐句）： 这项研究是为了改善乳腺癌的管理， 信息作为乳腺X线摄影的辅助手段，以帮助临床决策， 面对模棱两可的乳房X光片 早期的研究表明，微波辐射传感是一种很有前途的 当与乳房X光检查相结合时， 非癌性乳腺活检的基础上乳房摄影假阳性，从而 提高乳腺X线摄影的阳性预测值（PPV）。这些早期 研究将扩大到包括额外的临床研究中心， 如何提高系统性能，并提供更详细的 病理信息，这将有助于发现的原因， 热活动 通过更好地了解热异常的原因，我们可以 发现辐射或热传感的真正能力。 考虑到不必要的乳腺活检的高昂费用， 从情感上讲，利用热信息的系统应该被证明是非常重要的， 效益 拟定商业应用： 这项研究的长期目标是改善乳腺癌的管理 通过利用热信息作为乳房X线照相术的辅助手段， 在面对模棱两可的乳房X光检查时做出的决定。获得的数据 这项研究可能会导致改进的检测技术的发展， 基于非侵入性热传感的设备，作为乳房X线摄影的辅助设备。