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SOLUTION SCATTERING FROM COMPACT, DENATURED FORMS OF STAPHYLOCOCCAL NUCLEASE

SOLUTION SCATTERING FROM COMPACT, DENATURED FORMS OF STAPHYLOCOCCAL NUCLEASE
来自紧凑、变性形式的葡萄球菌核酸酶的溶液散射
批准号：
6658756
负责人：
EATON E LATTMAN
金额：
$14.32万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
项目状态：
已结题
起止时间：
2002-03-01 至 2003-02-28
来源：
https://reporter.nih.gov/project-details/6658756
关键词：
bioimaging /biomedical imaging biomaterials biomedical resource proteins radiography structural biology

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中文摘要
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英文摘要
We propose to make use of existing small angle X-ray scattering (SAXS) facilities at SSRL to carry out studies of protein folding intermediates encountered in mutants of staphylococcal nuclease and in the a subunit of tryptophan synthase. The studies push the limits of available technology both in terms of the time scale of kinetic experiments and in quality of the signal desired in the equilibrium experiments, where we hope to do quantitative analysis on samples containing mixtures of species. In particular we hope to use the new broad band pass multilayer recently tested on beamline 4-2 to increase intensity and decrease exposure times.
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Acquisition of Rigaku MicroMax-007 HF lab x-ray system
ZINC FINGER-DNA COMPLEX
  • 批准号：
    6977227
  • 项目类别：
  • 资助金额：
    $1.12万
  • 财政年份：
    2004
  • 负责人：
    EATON E LATTMAN
  • 依托单位：
    CORNELL UNIVERSITY
SOLUTION SCATTERING FROM COMPACT, DENATURED FORMS OF STAPHYLOCOCCAL NUCLEASE
  • 批准号：
    6586789
  • 项目类别：
  • 资助金额：
    $14.32万
  • 财政年份：
    2002
  • 负责人：
    EATON E LATTMAN
  • 依托单位：
    STANFORD UNIVERSITY
The Johns Hopkins Folding Meeting
  • 批准号：
    6323908
  • 项目类别：
  • 资助金额：
    $0.5万
  • 财政年份：
    2001
  • 负责人：
    EATON E LATTMAN
  • 依托单位：
    JOHNS HOPKINS UNIVERSITY
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