CHANGES IN DAILY STRESS AND WELL BEING

该提案寻求支持首次对成年期间的日常压力源和幸福感进行大规模纵向调查。主要目标是研究社会人口学因素、炉灶状况、个性特征和遗传天赋如何改变暴露在日常生活应激源中的变化模式，以及对这些应激源的身体和情感反应。其目的是：(1)描述日常压力源的多个方面(例如，频率、内容、严重性)与日常身体和情绪健康之间的联系 (2)研究个人因素，包括社会人口统计因素和个性特征，如何影响日常应激源暴露的变化以及身体和情感反应的变化；(3)调查每日应激源的暴露和反应如何与生理健康的生理指标相关，并预测全球健康报告中的变化；以及(4)探索相对遗传和环境影响，调节暴露和身体和情感反应的变化。 在整个成年过程中玩弄压力源。这些目标将通过在第一次数据收集大约10年后收集第二波全国日常经验研究(NSDE)来实现。NSDE是一项电话日记研究，对1483名年龄在25岁到74岁之间的美国成年人进行了全国抽样。NSDE中的受访者是MIDUS(美国中年生活)调查的代表性子样本。由MIDUS调查评估的一套丰富的预期和同时进行的社会人口学、身体健康和个性测量将用于预测NSDE从时间1到时间2对日常应激源的暴露以及身体和情感反应的变化。此外，来自拟议的MIDUS生物项目的数据将使我们能够检查在拟议的NSDE收集中测量的每日应激过程与健康的生理指标(例如，恒定负荷、免疫功能)之间的关系。所有这些问题都将在遗传信息样本中进行审查，以测试这些过程是如何受到遗传和环境影响的。

The proposal seeks support for the first large-scale longitudinal investigation of daily stressors and well-being during adulthood. The primary goal is to examine how sociodemographicfactors, hearth status, personality characteristics,and genetic endowment modify patterns of change in exposure to day-to-day life stressors as well as physical and emotional reactivity to these stressors. The aims are to : (1) describe how the links between multiple aspects of daily stressors (e.g., frequency, content, severity) and daily physical and emotional well-being change over 10 years during adulthood; (2) examine how personal factors, including sociodemographic factors and personality characteristics influence change in both exposure to as well as changes in physical and emotional reactivity to daily stressors; (3) investigate how exposure and reactivity to daily stressors correlate with physiological indicators of physical health and predict changes in global health reports; and (4) explore the relativegenetic and environmental influences mediating change in exposure and physical and emotional reactivity to dally stressors throughout adulthood. These aims will be addressed by collecting a second wave of the National Study of Daily Experiences (NSDE) approximately 10 years after the first data collection. The NSDE is a telephone diary study of a U.S. national sample of 1483 adults ranging in age from 25 to 74 years. Respondents in the NSDEare a representative subsample of the MIDUS (Midlife in the United States) survey. A rich set of prospective and concurrent sociodemographic, physical health, and personality measures assessed by the MIDUS survey will be used to predict change in exposure and physical and emotional reactivity to daily stressors from Time 1 to Time 2 of the NSDE. In addition, data from the proposed MIDUS biological project would allow us to examine how daily stress processes measured in the proposed NSDE collection are related to physiological indicators of health (e.g., allostatic load, immune functioning). All of these questions will be examined in a genetically informativesample to test how these processes are mediated by both genetic and environmental influences.