Race Differences in Female UI: Epidemiology and Biology

女性 UI 的种族差异：流行病学和生物学

• 批准号: 6660257
• 负责人: JOHN O.L. DELANCEY
• 金额: $ 35.11万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-19 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6660257
• 关键词: African American; caucasian American; clinical research; epidemiology; female; health surveys; human middle age (35-64); human subject; physiology; racial /ethnic difference; urethra; urinary bladder; urinary incontinence

DESCRIPTION (provided by applicant): The prevalence of urinary incontinence is often reported to be lower in black women than in white women. Whether or not this is true has not been confirmed in population based studies of younger women. In addition, the reasons for this prevalence difference are also unknown. This proposed population based, cross-sectional study will test the null hypothesis that no difference exists in the overall prevalence of urinary incontinence in black and white women. A telephone survey concerning occurrence of urinary incontinence (UT) and factors possible associated with UT will be administered to a regional sample of 1000 white women and 1500 black women age 30-60 years. A sub-sample of 130 black and white stress urinary incontinent, 100 black and white urge incontinent and 100 black and white continent women will undergo clinical testing in the form of pelvic floor testing to quantify bladder and urethra function. This survey will achieve the following aims: Aim lA: Define the prevalence of urinary incontinence in black and white women. Aim 1B: Determine the prevalence of stress and urge incontinence in black and white women. Aim 2: Identify demographic and personal factors that might explain the prevalence differences between the races. The clinical testing will accomplish the following aim. Aim 3: Compare the urethral and pelvic floor function of black and white women and continent and incontinent women. The survey and clinical components combined will achieve the final aim. Aim 4: Identify both epidemiologic and clinical factors associated with urinary incontinence. This research will confirm the reported race differences in the prevalence of urinary incontinence. It will also identify which epidemiologic and clinical factors contribute to this difference. Knowledge of these factors can then provide the basis for risk factor identification and the development of preventive strategies appropriate to different racial groups.

描述（由申请人提供）：尿失禁的患病率是 据报道，黑人女性的死亡率通常低于白色女性。是否 这一点在年轻人的人群研究中尚未得到证实。 妇女此外，造成这种患病率差异的原因也是 未知这项基于人群的横断面研究将测试 零假设，即泌尿系疾病的总体患病率无差异， 黑人和白色妇女的尿失禁。一项电话调查， 尿失禁（UT）的发生和可能与之相关的因素 UT将对1000名白色妇女和1500名 30-60岁的黑人妇女。130个黑人和白色压力的子样本 尿失禁，100个黑色和白色敦促失禁和100个黑色和 白色大陆妇女将接受临床测试的形式骨盆 地板测试以量化膀胱和尿道功能。本次调查将 达到以下目的：目的1A：确定泌尿系疾病的患病率， 黑人和白色妇女的尿失禁。目标1B：确定 黑人和白色妇女压力性和急迫性尿失禁。目标2：确定 可能解释患病率差异的人口统计学和个人因素 在种族之间。临床试验将实现以下目标。目的 3：比较黑人和白色女性的尿道和盆底功能， 大陆和失禁的女人。调查和临床成分相结合 将达到最终目的。目的4：确定流行病学和临床 尿失禁的症状有哪些这项研究将证实， 报告了尿失禁患病率的种族差异。它将 并确定哪些流行病学和临床因素促成了这一点 差对这些因素的了解可以为风险提供依据 确定因素和制定适当的预防战略 不同的种族群体。