The Epidemiology of Fecal Incontinence after Childbirth

大便失禁被认为是一种具有深远社会影响的常见疾病。 产科分娩被认为是导致女性大便失禁的主要原因。 目前还没有关于分娩后大便失禁的基于人群的研究;这是最高风险的时期。以前的研究检查产后大便失禁是从单一的机构，受转诊偏见的人群，和小的数字，使结果的普遍性是不可能的。该提案的主要目标是提供基于人群的发病率信息，以及与解剖/生理学结果和纵向随访基本相关的风险因素。 该提案的具体目标是：-提供基于人口的估计发生率大便失禁的所有产后妇女在俄勒冈州。- 确定导致产后大便失禁的可改变和不可改变的危险因素。- 深入探讨产科分娩方式和产后大便失禁之间可能的因果关系。- 建立一个产后大便失禁妇女队列，进行纵向随访，以确定预测症状缓解、复发或恶化可能性的因素。- 将解剖学和生理学发现与大便失禁症状联系起来。- 了解大便失禁的生理、心理和社会后果。这些数据将提供一个更好的了解问题的程度，并将提供数据，为未来的试验，预防和治疗大便失禁。

Fecal incontinence is thought to be a common condition with profound social impact. Obstetric delivery is thought to be the leading contributor to development of fecal incontinence in women. There are no population-based studies of fecal incontinence following childbirth; the highest-risk period. Previous studies examining postpartum fecal incontinence are from single institutions, populations that are subject to referral bias, and small numbers; making generalizability of the results impossible. The primary goal of this proposal is to provide population-based information on incidence, and risk factors with essential correlation with anatomic/physiologic findings and longitudinal follow-up. The specific aims of this proposal are to: - Provide population-based estimates of incidence of fecal incontinence in all postpartum women delivering in Oregon state. - Identify contributing modifiable and non-modifiable risk factors for the development of postpartum fecal incontinence. - Explore in depth a possible causal relationship between obstetric delivery methods and postpartum fecal incontinence. - Develop a cohort of women with postpartum fecal incontinence to follow longitudinally to identify factors that predict the likelihood of resolution, recurrence or worsening of symptoms. - Correlate anatomic and physiologic findings to symptoms of fecal incontinence. - Understand the physical, psychological, social ramifications of fecal incontinence. These data will provide a better understanding of the extent of the problem and will provide data essential for future trials of prevention and treatment of fecal incontinence.