Epigenetic reprogramming within the pluripotent lineage of the early embryo

早期胚胎多能谱系内的表观遗传重编程

• 批准号: nhmrc : 1066485
• 负责人: Prof Christopher O'Neill
• 金额: $ 44.21万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/epigenetic-reprogramming-pluripotent-early-embryo/455239
• 关键词: Epigenetic; reprogramming; within; pluripotent; lineage

Cells of the early embryo have the remarkable capacity to form all of the different tissues and organs in the body. This property requires re-organisation of the embryo’s genetic material in a manner analogous to re-booting a computer. This project will define the properties of this rebooting process. This information will allow much better strategies for building spare parts for regenerative medicine and provide the information required to reduce the incidence of inborn defects.

早期胚胎的细胞具有形成体内所有不同组织和器官的非凡能力。这种特性需要以类似于重启计算机的方式重组胚胎的遗传物质。这个项目将定义这个重启过程的属性。这些信息将为再生医学提供更好的策略，并提供减少先天性缺陷发生率所需的信息。