CENTER FOR STRUCTURAL AND FUNCTIONAL NEUROSCIENCE

结构和功能神经科学中心

• 批准号: 6529898
• 负责人: RICHARD J. BRIDGES
• 金额: $ 166.71万
• 依托单位: UNIVERSITY OF MONTANA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6529898
• 关键词: neurosciences

The long range goal of this project is to establish a Center of Biomedical Research Excellence that serves two primary function: i) to advance our understanding of Structural and Functional Neuroscience and ii) to increase the number of NIH-RO1-funded investigators in Montana. We propose to create a Center for Structural and Functional Neuroscience at the University of Montana using a well balanced combination of new faculty recruitment, development of needed instrumentation, and sub- project support for talented young faculty already in place. Research in the proposed Center will emphasize CNS protein structure and function as related to signal transduction, development and neurodegeneration. This thematic focus, not only builds on existing faculty strengths, but also represents a field in which interdisciplinary research at a growing University (without a medical school) can make a significant contribution to one of the highest priority health care issues facing our nation: understanding and lessening the burden of neurological diseases. The proposed Center will be developed using the following specific aims: Aim I - Enhance the critical mas of competitive neuroscientists at the University of Montana through strategic recruitment of three new faculty. Aim II - Promote the development of competitive neuroscience faculty through the support of individual subprojects Aim III - Enhance the infrastructure for neuroscience research through the acquisition of critically needed instrumentation for a shared core spectroscopy lab for studies of CNS protein structure and function. Aim IV - Establish a support network for Center neuroscientists that promotes infrastructure development, collaborative interaction and, most importantly, mentoring.

该项目的长期目标是建立一个生物医学卓越研究中心，该中心具有两个主要功能：i) 增进我们对结构和功能神经科学的理解；ii) 增加蒙大拿州 NIH-RO1 资助的研究人员数量。我们建议在蒙大拿大学创建一个结构和功能神经科学中心，平衡地结合新教师招聘、所需仪器的开发以及对现有的有才华的年轻教师的子项目支持。拟建中心的研究将强调与信号转导、发育和神经变性相关的中枢神经系统蛋白质结构和功能。这一主题重点不仅建立在现有师资力量的基础上，而且代表了一个领域，在这个领域中，成长中的大学（没有医学院）的跨学科研究可以为我们国家面临的最优先的医疗保健问题之一做出重大贡献：了解和减轻神经系统疾病的负担。拟议的中心将按照以下具体目标进行开发： 目标 I - 通过战略性招聘三名新教师，增强蒙大拿大学有竞争力的神经科学家的批判能力。目标 II - 通过支持各个子项目，促进有竞争力的神经科学教师的发展。 目标 III - 通过购买用于研究中枢神经系统蛋白质结构和功能的共享核心光谱实验室急需的仪器，增强神经科学研究的基础设施。目标 IV - 为中心神经科学家建立一个支持网络，促进基础设施发展、协作互动，以及最重要的指导。