RESEARCH TRAINING IN TRANSLATIONAL TUMOR IMMUNOLOGY

转化肿瘤免疫学研究培训

• 批准号: 6628504
• 负责人: JAMES J. MULE
• 金额: $ 23.14万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2006-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6628504
• 关键词: RESEARCH; TRAINING; TRANSLATIONAL; TUMOR; IMMUNOLOGY

DESCRIPTION (Applicant's Description): This application represents a new proposal for an NCI-sponsored program of "Research Training in Translational Tumor Immunology" at the University of Michigan. Faculty preceptors with interests in translational immunology have been selected from their primary D e p artments of Surgery, Medicine, Microbiology, Chemistry, Pathology, Radiation Oncology, and Laboratory Animal Medicine. These preceptors are also members of the new Graduate Program in Immunology and/or the Comprehensive Cancer Center's (CCC's) Tumor Immunology Program. Each of the 17 investiga- tors directs an active laboratory with a record of securing extramural support. Dr. James J. Mule will serve as the Program Director, and he will work closely with a Steering Committee to select trainees and formulate program policy. Predoctoral trainees will be enrolled in the Graduate Program in Immunology, which combines the resources of the Medical School, Graduate School, and CCC. The students will take courses in biochemistry, genetics, and immunology to prepare them for dissertation research with any of the preceptors. Postdoctoral trainees will devote their effort to full-time research. The proposed training program, through the Graduate Program in Immunology and the Tumor Immunology Program, will co-sponsor four major activities: a) a biweekly journal club at which trainees and preceptors meet for guided explorations of recent immunology papers; b) a monthly seminar series at which invited speakers from other universities, research institutes, and industry present research data and spend a day meeting with trainees and faculty; c) a Research Colloquium course, whose topic and instructor varies each semester; it allows graduate students (and postdoctoral auditors) to read about, and discuss in depth, a series of important topics in modern basic and translational immunology; and d) a scientific retreat held quarterly by the Tumor Immunology Program, at which faculty members present topic-related research data and collaborative efforts are established. Graduate students and postdoctoral fellows attend these retreats also. The program includes plans for training in research responsibility and for recruitment of underrepresented minority groups. Support is requested for four predoctoral and four postdoctoral trainees each year. Predoctoral and postdoctoral trainees should leave the program well prepared for academic careers focused on translational aspects of immunologic research as it pertains to the development of new strategies for the treatment of cancer.

描述（申请人描述）： 该应用程序代表了一种新的 国家癌症研究所资助的“翻译研究培训”项目的建议书 肿瘤免疫学”在密歇根大学。 学院导师， 翻译免疫学的兴趣已经从他们的主要选择 外科学、医学、微生物学、化学、病理学、 放射肿瘤学和实验动物医学。 这些导师也是 新的免疫学研究生课程和/或综合 癌症中心（CCC）肿瘤免疫学计划。 每一个17岁的孩子- 教师指导一个活跃的实验室， 支持. James J. Mule博士将担任项目主任，他将 与指导委员会密切合作，选择受训人员并制定 方案政策。 博士前实习生将参加研究生课程 在免疫学，它结合了医学院的资源，研究生 学校和CCC。 学生们将学习生物化学，遗传学， 和免疫学，为他们的论文研究做好准备， 导师 博士后将致力于全职工作 research. 拟议的培训方案，通过研究生方案， 免疫学和肿瘤免疫学计划，将共同赞助四个主要的 活动： a）每两周一次的日记俱乐部，学员和导师在那里聚会 对最近的免疫学论文进行指导性探索; B）每月一次的研讨会 邀请了来自其他大学，研究机构， 和行业展示研究数据，并花一天时间与学员会面， 教师; c）研究座谈会课程，其主题和讲师各不相同 每学期;它允许研究生（和博士后审计员）阅读 关于，并深入讨论，在现代基础和 转化免疫学;以及d）由 肿瘤免疫学计划，在该教员目前的主题相关 建立研究数据和协作努力。 研究生 和博士后研究员也参加这些务虚会。 该计划包括 计划 研究责任培训和招聘 代表性不足的少数群体。 申请资助4名博士生 每年培养4名博士后。 博士前和博士后 学员应离开该计划做好准备的学术生涯集中 关于免疫学研究的转化方面，因为它涉及到 开发治疗癌症的新策略。