ADOLESCENT MEDICINE TRIALS UNIT

纽约布朗克斯区阿尔伯特·爱因斯坦医学院蒙蒂菲奥里医学中心的青少年艾滋病项目(AAP)正在申请成为青少年医学艾滋病毒/艾滋病干预试验网络(ATN)中的青少年医学试验单位(AMTU)。AAP在为艾滋病毒阳性和高危青年提供最高质量的临床护理和研究方面拥有十多年的经验和领导能力。AAP位于纽约布朗克斯区，这是一个艾滋病毒和其他性传播感染比率非常高的地区。AAP已证明有能力维持100多名艾滋病毒阳性青年(累计超过225人)，其中大多数人通过性行为感染艾滋病毒，主要是有色人种青年，以及400多名有性经验的高危青年。AAP让100多名艾滋病毒阳性青年和100多名艾滋病毒阳性青年和1000多名艾滋病毒阴性青年参与了十多个多点研究的临床研究，包括艾滋病毒病程(REACH，NIH)、临床试验(ACTG，NIH)、行为干预(TLC，Clear，NIH)、危险行为分析(CDC)等。AAP计划在以下三个部分的基础上成为一个积极有效的AMU：1)一名经验丰富的首席调查员和三名研究协调员，他们在青少年医学艾滋病毒/艾滋病研究网络中建立和维护了第二活跃的网站，以及作为儿科艾滋病临床试验单位的长期历史和其他多地点研究的经验；20一个协调良好的综合护理团队，由在艾滋病毒护理和青少年健康方面经验丰富的医疗和心理健康从业者发起；以及3)一个创新的社区外联计划，包括成功的社会营销活动“艾滋病毒。与它共处。接受检测。”，与服务于高危青少年的社区机构建立牢固的关系。因此，AAP将在满足国家卫生研究院申请申请中提出的研究议程方面做出重要的科学和业务贡献。

The Adolescent AIDS Program (AAP) at Montefiore Medical Center of the Albert Einstein College of Medicine in the Bronx, New York is applying to be an Adolescent Medicine Trials Unit (AMTU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The AAP has more than a decade of experience and leadership in providing the highest quality clinical care and research with HIV-positive and at-risk youth. The AAP is located in the Bronx, New York, a locale with very high rate of HIV and other sexually transmitted infections. The AAP has a demonstrated ability yo maintain a cohort of more than one hundred HIV-positive youth (more than 225 cumulatively), the majority of whom have acquired HIV infection through sexual behaviors, and mostly youth of color, as well as a cohort of more than four hundred at-risk sexually experienced youth. The AAP has engaged more than one hundred HIV-positive youth and more than one hundred HIV-positive youth and more than 1000-HIV negative youth in clinical research in more than ten multi-site studies, including course of HIV disease (REACH, NIH), clinical trials (ACTG, NIH), behavioral interventions (TLC, CLEAR, NIH), risk behavior analyses (CDC) and others. The AAP plans to be an active and effective AMTU based on the following three components: 1) an experienced Principal Investigator and three Study Coordinators who have built and maintained the second most active site in the Adolescent Medicine HIV/AIDS Research Network, in addition to a long history as a Pediatric AIDS Clinical Trial Unit and experience in other multi-site studies; 20 a well-coordinated comprehensive care team started by medical and mental health practitioners experienced in HIV care and adolescent health; and 3) an innovative community outreach program, including the successful social marketing campaign "HIV. Live with it. Get Tested.", with strong relationships with community agencies serving at risk adolescents. Thus, the AAP will offer important scientific and operational contributions in meeting the research agenda posed in the Request for Applications by the National Institutes of Health.