ADOLESCENT MEDICINE TRIALS UNIT

位于纽约布朗克斯的阿尔伯特·爱因斯坦医学院Montefiore医学中心的青少年艾滋病项目（AAP）正在申请成为艾滋病毒/艾滋病干预青少年药物试验网络（ATN）中的青少年药物试验单位（AMTU）。AAP在为艾滋病毒阳性和高危青年提供最高质量的临床护理和研究方面拥有十多年的经验和领导能力。美国儿科学会位于纽约布朗克斯，这是一个艾滋病和其他性传播疾病感染率很高的地区。AAP已经证明有能力维持100多名艾滋病毒阳性青年（累计超过225人）的队列，其中大多数是通过性行为感染艾滋病毒的，其中大多数是有色人种的青年，以及400多名有危险的性经验的青年。AAP已在艾滋病疾病过程（REACH、NIH）、临床试验（ACTG、NIH）、行为干预（TLC、CLEAR、NIH）、风险行为分析（CDC）等十余项多站点研究中，参与了100余名HIV阳性青年、100余名HIV阳性青年和1000余名HIV阴性青年的临床研究。AAP计划成为一个活跃和有效的AMTU，基于以下三个组成部分：1)一位经验丰富的首席研究员和三位研究协调员，他们建立并维护了青少年医学艾滋病毒/艾滋病研究网络中第二活跃的站点，此外还有作为儿科艾滋病临床试验单位的悠久历史和其他多站点研究的经验；20 .由在艾滋病毒护理和青少年健康方面经验丰富的医疗和心理健康从业人员组建一个协调良好的综合护理小组；3)创新的社区外展计划，包括成功的社会营销活动“HIV”。接受它吧。进行检测”，并与社区机构建立了牢固的关系，为有风险的青少年提供服务。因此，AAP将在满足美国国立卫生研究院申请中提出的研究议程方面提供重要的科学和业务贡献。

The Adolescent AIDS Program (AAP) at Montefiore Medical Center of the Albert Einstein College of Medicine in the Bronx, New York is applying to be an Adolescent Medicine Trials Unit (AMTU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The AAP has more than a decade of experience and leadership in providing the highest quality clinical care and research with HIV-positive and at-risk youth. The AAP is located in the Bronx, New York, a locale with very high rate of HIV and other sexually transmitted infections. The AAP has a demonstrated ability yo maintain a cohort of more than one hundred HIV-positive youth (more than 225 cumulatively), the majority of whom have acquired HIV infection through sexual behaviors, and mostly youth of color, as well as a cohort of more than four hundred at-risk sexually experienced youth. The AAP has engaged more than one hundred HIV-positive youth and more than one hundred HIV-positive youth and more than 1000-HIV negative youth in clinical research in more than ten multi-site studies, including course of HIV disease (REACH, NIH), clinical trials (ACTG, NIH), behavioral interventions (TLC, CLEAR, NIH), risk behavior analyses (CDC) and others. The AAP plans to be an active and effective AMTU based on the following three components: 1) an experienced Principal Investigator and three Study Coordinators who have built and maintained the second most active site in the Adolescent Medicine HIV/AIDS Research Network, in addition to a long history as a Pediatric AIDS Clinical Trial Unit and experience in other multi-site studies; 20 a well-coordinated comprehensive care team started by medical and mental health practitioners experienced in HIV care and adolescent health; and 3) an innovative community outreach program, including the successful social marketing campaign "HIV. Live with it. Get Tested.", with strong relationships with community agencies serving at risk adolescents. Thus, the AAP will offer important scientific and operational contributions in meeting the research agenda posed in the Request for Applications by the National Institutes of Health.