Nebraska Redox Biology Center Renovation P20 RR17675

描述（由申请人提供）： 内布拉斯加州氧化还原生物学中心的总体目标是（一）通过指导初级教师取得成功，招募具有互补研究兴趣的新教师和战略性地加强生物医学研究基础设施，支持和扩大内布拉斯加州氧化还原生物学的现有优势;和（ii）创建一个全国可见和国际公认的中心，在COBRE赠款期限结束后，通过内部和外部-壁画的资金来源。该中心已开始为实现其目标作出必要努力，但面临一个关键的具体障碍，即实验室空间的改造，这对内布拉斯加大学林肯分校兽医和生物医学科学系招聘一名教员（微生物发病机理）至关重要。虽然这一翻修请求已列入原始提案，但项目主管的疏忽导致提供的平面图和预算理由信息不足，导致研究科建议将其从最终预算中删除。本申请的具体目的是通过获得必要的支持，将内布拉斯加州林肯大学兽医和生物医学科学系的现有储存空间改造和转换为实验室空间，以弥补这一不足，从而能够在微生物发病机理领域招聘一名教员。在内布拉斯加州氧化还原生物学中心的未来发展和成功的兽医和生物医学科学系的参与是重要的，部分原因是其两个成员在该中心的功能的积极参与。此外，拟议的微生物发病机理的聘用不仅将补充中心相关教师的专业知识，而且已被兽医和生物医学科学系独立确定为战略规划文件中的首要任务。

DESCRIPTION (provided by applicant): The overall goals of the Nebraska Redox Biology Center are to (i) buttress and expand the existing strengths in redox biology in Nebraska by mentoring junior faculty to success, recruiting new faculty with complementary research interests and strategically enhancing biomedical research infrastructure; and (ii) create a nationally visible and internationally recognized Center that will be sustained beyond the duration of the COBRE grant by intra- and extra-mural sources of funding. The Center has initiated efforts necessary to realize its goals but faces a key specific impediment, viz, renovation of laboratory space that is essential for recruitment of a faculty member (in microbial pathogenesis) to the Department of Veterinary and Biomedical Sciences at the University of Nebraska- Lincoln. While this request for renovation was included in the original proposal, an oversight on the Pl's part led to provision of insufficient information regarding floor plans and budget justification, and resulted in the recommendation by the study section for its deletion from the final budget. The specific aim of this application is to redress this deficiency by obtaining the requisite support for renovating and converting existing storage space in the Department of Veterinary and Biomedical Sciences at the University of Nebraska-Lincoln into laboratory space to enable recruitment of a faculty member in the area of microbial pathogenesis. The involvement of the Department of Veterinary and Biomedical Sciences in the future growth and success of the Nebraska Redox Biology Center is important, due in part to the active participation of two of its members in the Center's functions. Additionally, the proposed hire in microbial pathogenesis would not only complement the expertise of Center-associated faculty, but had been identified independently as the top priority in the strategic planning documents by the Department of Veterinary and Biomedical Sciences.