Examination of the role of biofilms in infection with enteropathogenic Escherichia coli

生物膜在致病性大肠杆菌感染中的作用的检查

• 批准号: nhmrc : 490901
• 负责人: A/Pr Cynthia Whitchurch
• 金额: $ 30.43万
• 依托单位: University of Technology Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/examination-role-biofilms-escherichia-coli/78346
• 关键词: Examination; role; biofilms; infection; enteropathogenic

Many infections are caused by bacteria living in communities, known as biofilms. Enteropathogenic E. coli (EPEC) is a major cause of diarrhoea and results in the death of millions of children annually. We have found a link between biofilm formation by EPEC and disease. In this project we will examine how biofilm formation by EPEC occurs and the contribution of biofilm formation to disease. The results of this study may indicate new ways to treat and prevent E. coli diarrhoea.

许多感染是由生活在社区中的细菌引起的，这种细菌被称为生物膜。致病性大肠杆菌(EPEC)是腹泻的主要原因，每年导致数百万儿童死亡。我们发现EPEC生物膜的形成与疾病之间存在联系。在这个项目中，我们将研究EPEC如何形成生物膜，以及生物膜形成对疾病的贡献。这项研究的结果可能会为治疗和预防大肠杆菌腹泻提供新的方法。