Environment and Neurodevelopmental Disorders

描述（由申请人提供） 这是一份会议补助申请，要求为将于2005年9月11日至14日在北卡罗来纳州研究三角公园举行的第二十二届国际神经毒理学会议（NTX XXII）提供部分资金。 第22届会议的主题是“环境与神经发育障碍”。本次会议的总体目标是汇集来自学术界，工业界，政府和非政府组织的专家，讨论已知的科学状况，确定信息差距，并帮助确定未来的研究方向，以推进我们对病因，机制，相关新技术，诊断，治疗和预防环境诱发或加重的儿童和成人神经系统疾病和紊乱。 一个中心主题是儿童和成人疾病或功能障碍的胎儿基础。 会议参与者将通过观察5个临床终点（自闭症，ADD，精神分裂症，帕金森病和阿尔茨海默病）来调查从“分子到（Wo）人”已知的内容;几类神经毒物（金属，PCB，农药，持久性有机污染物，溶剂）;和方法（分子事件，细胞变化，动物模型，人类功能障碍和流行病学研究）。 每届会议都将提出关于今后研究和研究需要的建议。

DESCRIPTION (provided by applicant) This is a conference grant application to request partial funding of the Twenty-Second International Neurotoxicology Conference (NTX XXII) to be held September 11-14, 2005 in Research Triangle Park, NC. The theme of the 22nd conference is "Environment and Neurodevelopmental Disorders". The overall objective of this conference is to bring together experts from academia, industry, governmental and nongovernmental organizations to discuss the state-of-the-science of what is known, identify information gaps, and help define future directions for research to advance our fundamental knowledge of the causes, mechanisms, related new technologies, diagnosis, treatment and prevention of environmentally induced or exacerbated diseases and disorders of the nervous system in children and adults. A central theme is the fetal basis of childhood and adult diseases or dysfunction. Conference participants will investigate what is known from "Molecule to (Wo)man" by looking at 5 clinical endpoints (autism, ADD, schizophrenia, Parkinson's disease and Alzheimer's disease; several categories of neurotoxicants (metals, PCBs, Pesticides, Pops, solvents); and Approaches (molecular events, cellular changes, animal models, human dysfunction and epidemiological studies). Recommendations for future studies and research needs will be articulated for each session.