Training Program in Molecular Oncology and Immunology

描述(由申请人提供)：本提案要求继续资助7名博士后和8名博士后研究员(博士或医学博士)在分子肿瘤学和免疫学领域的培训。特别强调这些学科的综合教育，以便更好地了解细胞转化和免疫细胞反应所涉及的调节机制。这些学科的交叉受精允许开发全新的方法来研究癌基因和处于正常状态或肿瘤中的免疫细胞，并促进癌症翻译研究的发展。该计划的独特之处在于，要求学员精通免疫学和分子肿瘤学的基础知识，然后指导学生专注于这两个领域中的一个，重点是与癌症相关的项目。来自病理学、细胞生物学、生物化学、药理学、医学系、放射肿瘤学、皮肤科、放射科和微生物系的38名教职员工参加了这个项目。该计划由萨克勒基础医学研究所和纽约大学癌症研究所共同主持，并扩大了斯基博尔生物分子医学研究所和A.戴蒙德免疫学教授的新教职。随着目前正在建设的Smilow大楼的开放，它将继续扩大规模，该大楼的三层将专门用于癌症研究。

DESCRIPTION (provided by applicant): This proposal requests funds to continue support for training of 7 predoctoral and 8 postdoctoral fellows (PhD or MD) in the areas of molecular oncology and immunology. Particular emphasis is placed on a combined education in these disciplines for a better understanding of the regulatory mechanisms involved in cellular transformation and immunological cell response. Cross-fertilization of these disciplines allows development of entirely new approaches to studies both of oncogenes and of immunologically cells in its normal state or in tumors and fosters the development of translational research in cancer. The unique aspects of this program is that the trainees are required to become proficient in the basics of both immunology and molecular oncology; the students are then directed to focus in one of these two areas with strong emphasis on cancer related projects. Thirty-eight faculty members from the Departments of Pathology, Cell Biology, Biochemistry, Pharmacology, Medicine, Radiation Oncology, Dermatology, Radiology and Microbiology participate in this program. The program is under the aegis of both the Sackler Institute for Basic Medical Sciences and the NYU Cancer Institute and has expanded with the new faculty recruited for the Skirball Institute of Biomolecular Medicine and the A. Diamond Professorships in Immunology. It will continue to expand with opening of the Smilow building, presently under construction, and which will dedicate three of its floors to cancer research.