Training in Drug Abuse and Brain Imaging

描述：(申请人提供)： 这是一项在中国建立博士后研究培训计划的建议 人类大脑成像和药物滥用领域。随着大脑十年的到来 两年前，我们掌握了一种更精致的大脑 成像工具。需要这样一个专门的程序是由 人类麸皮成像领域的爆炸性增长导致了 出现了新的和创新的技术来观察解剖学和 在各种情况下大脑的功能方面与 物质滥用，如急性醉酒效应，追踪线索诱导 渴望，测量认知效果，检测持续的神经和 认知缺陷，监测戒断，睡眠障碍，药物治疗 依从性，跟踪治疗进展和药物开发。因为 人脑成像涉及的子学科的性质和光谱如下 如此复杂，新一代具有脑科学背景的临床科学家 影像技术、神经科学、药理学、成瘾医学和 需要进行治疗以将脑成像领域与 探索药物滥用的神经生物学基础，从而填补 美国和国外研究中心的预期空缺--这 T32研究培训计划旨在填补这一空白。我们建议 建立综合的、多学科的药物滥用和脑成像 由McLean共同支持的培训计划(DABITP) 医院/哈佛医学院和波士顿大学医学院。这个 这些项目的成功在很大程度上是基于许多人的高素质 有才华的教职员工和当前的实习生群体。与一个 显著交叉培养思想和学生的环境，以及 经过验证的积极和富有成效的协作记录，是实现以下目标的基础 一项努力已经很好地到位了。拟议的三年制博士后 培训计划将被组织起来，为学员提供 磁共振的基本原理和脑的电生理测量 活动(第一年)，然后安排三个不同设计的课程之一 符合学员未来职业目标的研究跟踪：1)MR Technology 和仪器跟踪；2)基础临床研究跟踪；3)临床 治疗赛道。脑部影像教学训练与心理健康教育的结合 精神药理学在各种高度的实际应用中的应用 成功的研究实验室将为我们提供下一代 药物滥用研究人员，他们有能力使用脑成像技术 他们开始对上瘾的大脑进行下一个十年的研究。

DESCRIPTION: (Provided by Applicant): This is a proposal to establish a postdoctoral research training program in the field of human brain imaging and drug abuse. As the Decade of the Brain came to a close two years ago, we have at our disposal a more refined variety of brain imaging tools. The need for such a dedicated program is dictated by the explosive growth of the field of human bran imaging that has led to an emergence of new and innovative techniques to view both the anatomical and functional aspects of the brain under a variety of conditions related to substance abuse such as acute intoxicating effects, tracking cue-induced craving, measuring cognitive effects, detecting persistent neurological and cognitive defects, monitoring withdrawal, sleep disturbances, medication compliance, tracking treatment progress and medication development. Because the nature and spectrum of the sub-disciplines involved in human brain imaging are so complex, a new breed of clinical scientists with backgrounds in brain imaging technology, neuroscience, pharmacology, addiction medicine and treatment will be needed to integrate the fields of brain imaging with the exploration of the neurobiological bases of drug abuse and thus fill the anticipated vacancies in research centers in the United States and abroad--this T32 Research Training Program is designed to fill this void. We propose to establish an integrated, multidisciplinary Drug Abuse and Brain Imaging Training Program (DABITP) to be jointly supported by the McLean Hospital/Harvard Medical School and Boston University School of Medicine. The success of these programs is based largely on the high caliber of the many talented faculty members and current group of trainees. Together with an environment of significant cross fostering of ideas and students as well as a proven record of active and productive collaboration, the foundation for such an endeavor is already well in place. The proposed three year post doctoral training program will be structured to provide the trainees with the fundamentals of magnetic resonance and electrophysiological measures of brain activity (year 1), followed by placement in one of three distinctly designed research tracks that meets the trainees future career goals: 1) MR Technology and Instrumentation Track; 2) Basic Clinical Research Track; and 3) Clinical Treatment Track. The combination of didactic training in brain imaging and psychopharmacology with practical applications in a variety of highly successful research laboratories will provide us with the next generation of drug abuse researchers who are equipped to employ brain imaging techniques as they embark on the next decade of research on the addicted brain.