Research Training in Digestive Diseases

描述（由申请人提供）： 在UVa的GI培训计划继续致力于发展研究人员致力于学术胃肠病学的职业生涯。该培训计划的基础是一个强大的研究环境，在过去5年中，该环境在规模，资金和生产力方面稳步增长。该计划旨在培养新一代高质量的胃肠病学学术研究人员。博士后培训课程的基本特征包括参与直接的基础和临床研究，以及旨在提供生物医学科学坚实基础和最新研究技术的教学指导和丰富活动的综合计划。研究领域和范围：该培训计划的一个中心特点是热情的研究人员的领导应用国家的最先进的技术，在胃肠道健康和疾病的基本问题。教师的广泛的研究兴趣是由相关学科的核心统一的，这是共同的每个学员的经验。大多数学员将接受实验室研究培训，将分子生物学，遗传学和免疫学的工具应用于重要的GI问题。培训提供了几个学科：免疫学，分子生物学，信号转导，生理学，癌症生物学，遗传学和流行病学/健康评估科学。对于追求临床调查的学员，在定量科学，包括结果研究，生物统计学，流行病学和临床试验严格的课程也可与健康评估科学学院合作。培训水平，背景和培训人数：此继续申请的重点是为持有医学博士学位的个人提供博士后培训，博士，或相关学位。要求四个博士后职位，每年有2个开始培训，并在该奖项支持的培训中至少保留2年。由于我们计划的成功，我们要求增加一个职位的总人数。四个为期10周的夏季博士前职位也被要求扩大我们的计划。培训设施：研究培训将在研究导师的现有实验室进行，研究导师是一组具有广泛协作互动的既定研究人员。实验室位于消化健康研究中心，这是UVa健康系统校园的一部分，包括近50万平方英尺的最先进的研究空间。过去的成就和对消化健康研究的影响：这个培训补助金一直在消化健康研究在UVa的发展工具。在过去的资助期间，我们资助了9名学员。目前有5人仍在接受培训。完成培训的4人中有3人担任助理教授的学术职务，1人进入医学院。在我们的9名受训人员中，2名是妇女，2名是少数民族。目前正在接受培训的所有5名受训人员都计划从事学术医学事业。

DESCRIPTION (provided by applicant): The GI Training Program at UVa continues to be committed to developing investigators dedicated to careers in academic gastroenterology. The foundation of this training program is a robust research environment, which has grown steadily over the past 5 years in size, funding, and productivity. The program is designed to produce a new generation of high quality academic investigators in gastroenterology. Fundamental features of the post-doctoral training curriculum include participation in direct basic and clinical research and a comprehensive program of didactic instruction and enrichment activities aimed at providing a solid foundation in biomedical sciences as well as the latest research techniques. Research Areas and Disciplines: A central feature of the training program is the leadership of enthusiastic investigators applying state-of-the-art techniques to fundamental questions in gastrointestinal health and disease. The broad range of research interests of the faculty is unified by a core of related disciplines, which are common to every trainee's experience. The majority of trainees will undergo training in laboratory research, applying the tools of molecular biology, genetics, and immunology to important GI questions. Training is offered in several disciplines: Immunology, Molecular Biology, Signal Transduction, Physiology, Cancer Biology, Genetics, and Epidemiology/Health Evaluation Sciences. For the trainees pursuing clinical investigation, a rigorous curriculum in quantitative sciences, including Outcomes Research, Biostatistics, Epidemiology, and Clinical Trials is also available in collaboration with the Health Evaluations Sciences faculty. Level of Training, Background, and Number of Trainees: This continuation application is focused on post-doctoral training offered to individuals holding M.D., Ph.D., or relevant degrees. Four post-doctoral positions are requested, with 2 beginning training each year and remaining in training supported by this award for a minimum of 2 years. Due to the success of our program, we are requesting to increase the total number of positions by one position. Four 10-week summer pre-doctoral positions are also requested to expand our program. Training Facilities: Research training will take place in the existing laboratories of the research mentors, a group of established investigators with extensive collaborative interactions. Laboratories are located in the Digestive Health Research Center, which is part of the UVa Health System campus that includes almost 500,000 square feet of state-of-the-art research space. Past Accomplishments and Impact on Digestive Health Research: This training grant has been instrumental in the development of digestive health research at UVa. During the past funding period, we have supported 9 trainees. Five are currently still engaged in training. Three of the 4 individuals who have finished training have taken academic positions as assistant professors and 1 has entered medical school. Of our 9 trainees, 2 were women and 2 were minorities. All 5 trainees currently in training are planning to pursue careers in academic medicine.